ABC100
Anti-Hyaluronan synthase 3 Antibody
from rabbit, purified by affinity chromatography
別名:
Hyaluronan synthase 3, Hyaluronate synthase 3, Hyaluronic acid synthase 3, HA synthase 3
製品名
Anti-Hyaluronan synthase 3 Antibody, from rabbit, purified by affinity chromatography
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... HAS3(3038)
Analysis Note
Control
SW620 cell lysate
SW620 cell lysate
Evaluated by Western Blot in SW620 cell lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected Hyaluronan synthase 3 on 10 µg of SW620 cell lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected Hyaluronan synthase 3 on 10 µg of SW620 cell lysate.
Application
Detect Hyaluronan synthase 3 using this Anti-Hyaluronan synthase 3 Antibody validated for use in Western Blotting & IHC.
Immunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected Hyaluronan synthase 3 in human liver and human kidney tissues.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
Biochem/physiol Actions
This antibody recognizes both isoforms at the cytoplasmic domain of Hyaluronan synthase 3.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Hyaluronan synthase 3 (HAS3) is one of three enzymes, located at the plasma membrane, that synthesizes the glycosaminoglycan hyaluronan. Hyaluronan is involved in cell proliferation, differentiation, angiogenesis, and tumor development, among other cellular processes. Hyaluronan synthase 3 creates the low—molecular-weight hyaluronan, whereas hyaluronan synthase 1 and 2 create high molecular weight isoforms.
~28/60 kDa observed. An uncharacterized band appears at ~70 kDa in some lysates. The calculated molecular weight of this protein is 63 kDa for isoform 1 and 31 kDa for isoform 2, but can be observed at ~60 and ~28 kDa
Immunogen
Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Hyaluronan synthase 3.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
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保管分類
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
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