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Merck

ABE1007

Anti-BATF3 Antibody

from rabbit, purified by affinity chromatography

別名:

Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, Jun dimerization protein p21SNFT

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
FACS, WB
Citations:
1
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

flow cytometry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... BATF3(55509)

General description

BATF3, also known as Basic leucine zipper transcriptional factor ATF-like 3, B-ATF-3, 21 kDa small nuclear factor isolated from T-cells, or Jun dimerization protein p21SNFT, and encoded by the gene BATF3/SNFT, is an AP-1 family transcription factor that controls the differentiation of CD8+ thymic conventional dendritic cells in the immune system. BATF3 is required for the development of CD8-alpha+ classical dendritic cells (cDCs) and related CD103+ dendritic cells that cross-present antigens to CD8. BATF3 acts via the formation of a heterodimer with JUN family proteins that recognizes and bind the DNA sequence 5′-TGA[CG]TCA-3′ and thus regulates the expression of the target genes. BATF3 is localized to the nucleus. BATF3 is expressed in myeloid dendritic cells and T cell precursor immune cells primarily.
~17 kDa observed

Immunogen

Epitope: Leucine-zipper
KLH-conjugated linear peptide corresponding to the Leucine-zipper of human BATF3.

Application

Detect BATF3 using this Anti-BATF3 antibody validated for use in western blotting & flow cytometry.
Flow Cytometry Analysis: 1 µg of this antibody detected BATF3 in human PBMC cells.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Nuclear Receptors

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected BATF3 in 10 µg of human spleen tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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保管分類

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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