Anti-mHUMMR Antibody

Hypoxia up-regulated mitochondrial movement regulator (HUMMR), a novel mitochondria protein, is expressed in neurons and is markedly induced by hypoxia-inducible factor 1 α (HIF-1α). HUMMR interacts with Miro-1 and Miro-2, mitochondrial proteins that are critical for mediating mitochondrial transport. Knockdown of HUMMR or HIF-1 function in neurons exposed to hypoxia markedly reduces mitochondrial content in axons.

~ 45 kDa observed. 50 kDa calculated.

Epitope: Unknown

Linear peptide corresponding to mouse HUMMR.

Anti-mHUMMR Antibody is an antibody against mHUMMR for use in WB.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

This antibody recognizes mouse HUMMR protein

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Mouse testis lysate

Evaluated by Western Blot in mouse testis lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected HUMMR on 10 µg of mouse testis lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.