Anti-FEZ2 Antibody

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

~38/50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.

KLH-conjugated linear peptide corresponding to human FEZ2.

Detect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.

Immunofluorescence Analysis: 5 µg/mLfrom a representative lot detected FEZ2 in human brain tissue.

Research Category
Neuroscience

Neuroscience

Research Sub Category
Developmental Neuroscience

Neuroregenerative Medicine

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
3T3 cell lysate

Evaluated by Western Blot in 3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FEZ2 in 15 µg of 3T3 cell lysate.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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