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Merck

ABN472

Anti-TFEB Antibody

from rabbit, purified by affinity chromatography

別名:

Transcription factor EB, Class E basic helix-loop-helix protein 35, bHLHe35, TFEB

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
-
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... TFEB(7942)

General description

Transcription factor EB (TFEB) is a member of the MiT/TFE family of transcription factors that is translocated in a subset of renal tumors. It plays an important role in the signal transduction process required for normal vascularization of the placenta. TFEB specifically recognizes and binds the E-box sequence (5′-CANNTG-3′) and CLEAR box sequence (5′-GTCACGTGAC-3′).
~57 kDa observed. Uniprot describes two isoforms at ~44 kDa and ~53 kDa Uncharacterized bands may appear in some lysates.

Immunogen

KLH-conjugated linear peptide corresponding to human TFEB.

Application

Detect TFEB using this rabbit polyclonal antibody, Anti-TFEB Antibody validated for use in western blotting.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases

Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
A549 cell lysate
Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TFEB in 15 µg of A549 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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保管分類

12 - Non Combustible Liquids

wgk

WGK 2



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