ABN58
Anti-phospho MAP1B (Thr1265) Antibody
from rabbit, purified by affinity chromatography
別名:
Microtubule-associated protein 1B, MAP-1B, MAP1(X), MAP1.2, MAP1 light chain LC1
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
rat
Application:
ICC, IHC, WB
Citations:
-
biological source
rabbit
Quality Segment
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
species reactivity (predicted by homology)
mouse (immunogen homology)
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pThr1265)
Gene Information
mouse ... Map1B(17755)
rat ... Map1B(29456)
General description
Microtubule-associated protein 1B (MAP1B) is neuron-specific and is thought to play a part in controlling the neuronal cytoskeleton. MAP1B is made up of heavy and light chains and is involved in the microtubule and actin filament association. MAP1B may have an important role in axon formation by supporting microtubule dynamics and controlling cytoskeletal arrangement. MAP1B has also been associated with Netrin 1 signaling.
~300 kDa observed
Immunogen
Epitope: Phosphorylated Thr1265
KLH-conjugated linear peptide corresponding to mouse MAP1B phosphorylated at Thr1265.
Application
Anti-phospho MAP1B (Thr1265) Antibody is an antibody against phospho MAP1B (Thr1265) for use in WB, IH & IC.
Immunohistochemistry Analysis: 1:600 dilution from a representative lot detected MAP1B in embryonic (E12) rat spinal cord tissue. (Image courtesy of Dr. Phillip R. Gordon-Weeks, King′s College London.)
Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (Trivedi, N., et al. (2005). Journal of Cell Science. 118:993-1005.)
Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (Trivedi, N., et al. (2005). Journal of Cell Science. 118:993-1005.)
Biochem/physiol Actions
Other homologies: Human (91% sequence homology).
This antibody recognizes MAP1B phosphorylated at Thr1265.
Analysis Note
Control
S1 rat brain tissue lysate
S1 rat brain tissue lysate
Evaluated by Western Blot in S1 rat brain tissue lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected MAP1B on 10 µg of S1 rat brain tissue lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected MAP1B on 10 µg of S1 rat brain tissue lysate.
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保管分類
12 - Non Combustible Liquids
wgk
WGK 2