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ABS14

Anti-PKA RII Beta Antibody

Name: Anti-PKA RII Beta Antibody
Brand: MM

from rabbit, purified by affinity chromatography

別名:

protein kinase, cAMP-dependent, regulatory, type II, beta, cAMP-dependent protein kinase type II-beta regulatory chain, cAMP-dependent protein kinase type II-beta regulatory subunit

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この商品について

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

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特性

biological source

rabbit

Quality Segment

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human, horse

species reactivity (predicted by homology)

bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), canine (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), equine (based on 100% sequence homology)

technique(s)

western blot: suitable

NCBI accession no.

NP_002727

UniProt accession no.

P31323

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PRKAR2B(5577)

詳細

General description

PKA RII Beta is a type two regulatory chain which mediates membrane association by binding to anchoring proteins, including the MAP2 kinase. When the enzyme is inactive there are two regulatory chains and two catalytic chains. PKA RII Beta is activated by cAMP and produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules.

~ 46 kDa observed

Immunogen

Epitope: cAMP2 domain

KLH-conjugated linear peptide corresponding to human PKA RII Beta at the cAMP2 domain.

Application

Anti-PKA RII Beta Antibody is an antibody against PKA RII Beta for use in WB.

Research Category
Signaling

Research Sub Category
Kinases & Phosphatases

Western Blot Analysis: 0.5 µg/mL from a previous lot detected PKA RII Beta on 10 µg of mouse brain tissue lysate.

Biochem/physiol Actions

This antibody recognizes PKA RII Beta at the cAMP2 domain.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human brain tissue lysate

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected PKA RII Beta on 10 µg of human brain tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類

12 - Non Combustible Liquids

一体何が起きているの？

WGK 1

引火点 (F)

Not applicable

引火点（°C）