RANTES Protein, Human Recombinant Animal Free

RANTES , also known as CCL5, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Product is filtered through a 0.2 micron filter before lyophilization.

Store at -20°C for up to 6 months from date of receipt.

Bioactivity assay: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.

Recombinant animal free human RANTES is manufactured using all non-animal reagents

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.