Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD

TAOK1 , also known as Serine/threonine-protein kinase TAO1, Kinase from chicken homolog B, hKFC-B, MARK Kinase, MARKK, Prostate-derived sterile 20-like kinase 2, PSK-2/PSK2, Prostate-derived STE20-like kinase 2, or Thousand and one amino acid protein kinase 1, TAOK1/hTAOK1, and encoded by the gene TAOK1/KIAA1361/MAP3K16/MARKK, is an important serine/threonine protein kinase involved in a variety of processes including p38/MAPK14 stress responses, DNA damage responses and cytoskeleton stability. TAOK1 also acts as regulator of apoptosis and controls the morphological changes associated with apoptosis including cell contraction, membrane blebbing and apoptotic body formation. TAOK1 is expressed in many tissues but highly expressed in testis as well as brain, colon and muscle. TAOK1 is localized to the cytoplasm and a target for caspase-3 as well as SPRED1 a regulator of the MAP kinase cascade.

~116 kDa observed

Epitope: C-terminus

Linear peptide corresponding to the C-terminus of human TAOK1.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-TAOK1 Antibody (long isoform), clone TAO1_1.2_VMD is validated for use in Western Blotting for the detection of TAOK1 (long isoform).

Western Blotting Analysis: A representative lot detected TAOK1 in HeLa cell lysate, but not in TAOK1 siRNA transfected HeLa cell lysate (Prof. Viji Draviam, University of Cambridge).

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected TAOK1 in 10 µg of HeLa cell lysate.

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