Anti-Somatotropin/GH1 Antibody, clone 1H1.1

Somatotropin (UniProt P01241; also known as GH, GH-N, Growth hormone 1, hGH-N, Pituitary growth hormone) is encoded by the GH1 (also known as GH, GHN, IGHD1B) gene (Gene ID 8856) in human. Somatotropin is a peptide hormone that plays an important role in growth control by inducing IGF-1 secretion in liver and other tissues. It stimulates myoblast differentiation and proliferation, as well as amino acids uptake and protein synthesis in muscle and other tissues. Acromegaly is a rare endocrine syndrome caused by a GH-secreting pituitary adenoma. Acromegaly may also be rarely associated with a hypothalamic or an ectopic GH-releasing hormone-producing tumor.

~25 kDa observed. This protein has several isoforms from ~20-25 kDa

GST-tagged recombinant protein corresponding to human Somatotropin/GH1.

Anti-Somatotropin/GH1 Antibody, clone 1H1.1 is an antibody against Somatotropin/GH1 for use in Western Blotting.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Expected to react with isoforms 1, 3, and 4. Reactivity to isoforms 2 and 5 have not been tested.

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human pituitary tissue lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Somatotropin/GH1 in 10 µg of human pituitary tissue lysate.

Concentration: Please refer to lot specific datasheet.

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