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Merck

MABE441

Anti-HJURP Antibody, clone 144K/B1

clone 144K/B1, from mouse

別名:

Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9, HJURP

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この商品について

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
144K/B1, monoclonal
Application:
ChIP, IP, WB
Citations:
1
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biological source

mouse

Quality Segment

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

144K/B1, monoclonal

species reactivity

human

technique(s)

ChIP: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG2bκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... HJURP(55355)

General description

Holliday junction recognition protein (HJURP) is also known as 14-3-3-associated AKT substrate (FAKTS), Fetal liver-expressing gene 1 protein (FLEG1) and Up-regulated in lung cancer 9 (URLC9). HJURP is a centromeric protein that acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. HJURP is highly expressed in the thymus, testis, and in many lung cancer samples with lower levels found in placenta, small intestine, liver, skeletal muscle, and colon.
~90 kDa observed

Immunogen

Recombinant protein corresponding to human HJURP.

Application

Detect Holliday junction recognition protein using this mouse monoclonal antibody, Anti-HJURP Antibody, clone 144K/B1 validated for use in western blotting & IP.
Immunoprecipitation Analysis: A representative lot immunoprecipitated HJURP in HeLa nuclear extract (Ana Losada, CNIO, Madrid, Spain).

Chromatin Immunoprecipitation (ChIP) Analysis: A representative lot immmunoprecipitated HJURP in HEK293 cell lysate (Ana Losada, CNIO, Madrid, Spain).

Physical form

Format: Purified

Analysis Note

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected HJURP in 10 µg of HEK293 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


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保管分類

12 - Non Combustible Liquids

一体何が起きているの?

WGK 1

引火点 (F)

Not applicable

引火点(°C)

Not applicable



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