MABN119
Anti-KLF6 Antibody, clone 12A8.3
clone 12A8.3, from mouse
別名:
Krueppel-like factor 6, B-cell-derived protein 1, Core promoter element-binding protein, GC-rich sites-binding factor GBF, Proto-oncogene BCD1, Suppressor of tumorigenicity 12 protein, Transcription factor Zf9
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この商品について
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
12A8.3, monoclonal
Application:
IHC, WB
Citations:
2
biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
12A8.3, monoclonal
species reactivity
mouse, human
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG2bκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... KLF6(1316)
General description
KLF6 (Krueppel-like factor 6), is also known as BCD1, COPEB, CPBP and ST12. KLF6 contains zinc-finger domains and is thought to be a transcriptional activator binding to GC box motifs. KLF6 is involved in B-cell growth and development and has been shown to be highly expressed in placental cells as well as other tissues including the spleen, thymus, prostate, testis, small intestine and colon. KLF6 defects have been linked to gastric cancer (GASC) and prostate cancer (PC).
~37 kDa observed. The calculated molecular weight is 32 kDa, however KLF6 has been shown at ~37 through ~40 kDa bands in western blots (Kimmeleman, A. C., et al. (2004). Oncogene. 23:5077-5083).
Immunogen
GST-tagged recombinant protein corresponding to human KLF6.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Signaling
Developmental Signaling
This KLF6 antibody is validated for use in WB & IHC for the detection of the KLF6 protein.
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected KLF6 in 10 µg of human placenta tissue lysate.
Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected KLF6 in human placenta tissue.
Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected KLF6 in human placenta tissue.
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control
NIH-3T3 cell lysate
NIH-3T3 cell lysate
Evaluated by Western Blotting in NIH-3T3 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected KLF6 in 10 µg of NIH-3T3 cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected KLF6 in 10 µg of NIH-3T3 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable