MABT61
Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302
clone R1.302.12, from mouse
å¥å:
poliovirus receptor-related 1 (herpesvirus entry mediator C), nectin-1, poliovirus receptor-related protein 1, poliovirus receptor-like 1, nectin 1, ectodermal dysplasia 4 (Margarita Island type), Herpesvirus entry mediator C, Herpes virus entry mediator
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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
R1.302.12, monoclonal
Application:
FACS, IF
Citations:
-
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ãæäŒãããŸãbiological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
R1.302.12, monoclonal
species reactivity
human
technique(s)
flow cytometry: suitable, immunofluorescence: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PVRL1(5818)
General description
57 kDa calculated
Nectin-1, also known as poliovirus receptor-related protein 1 (PRR1 or PVRL1) or CD111, is an immunoglobulin-like transmembrane cell adhesion protein that also seems to play a role in neural tube formation, with N-cadherin. Nectins are known for being the receptors for the herpes simplex virus. Nectin-1 is connected with the actin cytoskeleton through afadin inside the cell. It is predominantly found in human placenta although in mice, expression is wide-ranging. Nectin-1 seems to adhere primarily to cells expressing nectin-4 and vice versa.
Immunogen
Human CD111 transfected NIH/3T3 cells
Application
Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Cocchi, F., et al. (1998). Journal of Virology. 72(12):9992â10002).
This Anti-Nectin-1/PVRL1 (CD111) Antibody, clone R1.302 is validated for use in FC, IF for the detection of Nectin-1/PVRL1 (CD111).
Physical form
Format: Purified
Analysis Note
Control
Human TF-1 cells
Human TF-1 cells
Evaluated by Flow Cytometry in human TF-1 cells.
Flow Cytometry Analysis: 0.25 µg of this antibody detected Nectin-1/PVRL1 in human TF-1 cells.
Flow Cytometry Analysis: 0.25 µg of this antibody detected Nectin-1/PVRL1 in human TF-1 cells.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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WGK
WGK 1
åŒç«ç¹ (F)
Not applicable
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Not applicable
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