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Merck

AB3796

Anti-5′-Lipoxygenase Antibody

Chemicon®, from rabbit

동의어(들):

Arachidonate 5-lipoxygenase, 5-LO

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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제품 이름

Anti-5′-Lipoxygenase Antibody, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rabbit, rat, mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ALOX5(240)

Analysis Note

Control
POSITIVE CONTROL: placenta, lung, and leukocytes.

Application

Anti-5′-Lipoxygenase Antibody detects level of 5′-Lipoxygenase & has been published & validated for use in ELISA, IP & WB.
Western blot: 1:1,000. Reacts with a 79 kDa band
Immunoprecipitation: 5 μL/mL lysate
ELISA: 1:1000 – 1:100,000
Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

5′-Lipoxygenase

General description

5′-Lipoxygenase is a critical enzyme in the formation of leukotrienes from arachidonic acid. Upon activation, the enzyme translocates to either a nuclear or plasma membrane compartment.

Immunogen

Purified human 5′-Lipoxygenase

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin in PBS with 50% Glycerol and 0.02% sodium azide

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 2


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Fen Yin et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(6), 1153-1161 (2013-04-06)
To evaluate whether exposure to air pollutants induces oxidative modifications of plasma lipoproteins, resulting in alteration of the protective capacities of high-density lipoproteins (HDLs). We exposed apolipoprotein E-deficient mice to diesel exhaust (DE) at ≈ 250 µg/m(3) for 2 weeks
Anna M Adamusiak et al.
International archives of allergy and immunology, 157(4), 354-362 (2011-11-30)
The pathogenesis of rhinosinusitis in aspirin-exacerbated airway disease is closely linked to the disequilibrium in arachidonic acid metabolism. Although considerable amounts of data concerning impaired eicosanoid production are available, the precise mechanism and pathogenesis of the disease are still unknown.
Daryle J DePianto et al.
JCI insight, 6(8) (2021-03-12)
Compromised regenerative capacity of lung epithelial cells can lead to cellular senescence, which may precipitate fibrosis. While increased markers of senescence have been reported in idiopathic pulmonary fibrosis (IPF), the origin and identity of these senescent cells remain unclear, and

국제 무역 품목 번호

SKUGTIN
AB379604053252744365

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