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Merck

CBL186

Anti-DNA Antibody, clone AC-30-10

clone AC-30-10, Chemicon®, from mouse

동의어(들):

Deoxyribonucleic acid

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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제품 이름

Anti-DNA Antibody, clone AC-30-10, clone AC-30-10, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

AC-30-10, monoclonal

species reactivity (predicted by homology)

all

manufacturer/tradename

Chemicon®

technique(s)

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

isotype

IgM

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Application

Anti-DNA Antibody, clone AC-30-10 is a Mouse Monoclonal Antibody for the detection of DNA & has been validated in IF, IHC(P).
Research (cell biology, molecular biology, microbiology) since it reacts with any form of native and denatured DNA. Reliable positive control in immunofluoresence assays for detecting DNA antibodies on tissues of cultured cells, notably in the diagnosis of autoantibodies and autoimmune diseases.

Sensitive detection of mycoplasma contamination in cell cultures.
For frozen and paraffin tissue sections.

Optimal working dilutions must be determined by the end user.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

This antibody reacts with native denatured DNA extracted from various organisms: mouse DNA, calf thymus DNA, M13 DNA, SV-40 DNA and several plasmids. It also reacts with synthetic DNA of different base compositions: poly dAT-poly dAT, poly dAT. DNA-containing structures such as chromatin in diverse tissues from several species as well as in diverse cell lines such as XLKE-A6 (Xenopus), RVF-SMC (rat kangaroo) and HeLa (human) are also recognized.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Physical form

Format: Purified
The immunoglobulin was purified by gel filtration and presented in PBS, pH 7.4, containing 0.09% sodium azide and 0.5% BSA.

Preparation Note

Maintain at 2-8°C for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Ya-Jing Li et al.
Acta pharmacologica Sinica, 43(8), 2026-2041 (2022-01-15)
Liver fibrosis is the common consequence of almost all liver diseases and has become an urgent clinical problem without efficient therapies. Recent evidence has shown that hepatocytes-derived extracellular vesicles (EVs) play important roles in liver pathophysiology, but little is known
Genome-wide analysis reveals coating of the mitochondrial genome by TFAM.
Wang, YE; Marinov, GK; Wold, BJ; Chan, DC
Testing null
Pedro Silva-Pinheiro et al.
Nucleic acids research, 49(9), 5230-5248 (2021-05-07)
Mutations in POLG, encoding POLγA, the catalytic subunit of the mitochondrial DNA polymerase, cause a spectrum of disorders characterized by mtDNA instability. However, the molecular pathogenesis of POLG-related diseases is poorly understood and efficient treatments are missing. Here, we generate
Sebastian Aguirre et al.
Nature microbiology, 2, 17037-17037 (2017-03-28)
During the last few decades, the global incidence of dengue virus (DENV) has increased dramatically, and it is now endemic in more than 100 countries. To establish a productive infection in humans, DENV uses different strategies to inhibit or avoid
Andong Qin et al.
Cells, 12(21) (2023-11-10)
Coxsackievirus B3 (CVB3), a single-stranded positive RNA virus, primarily infects cardiac myocytes and is a major causative pathogen for viral myocarditis (VMC), driving cardiac inflammation and organ dysfunction. However, whether and how myocardial damage is involved in CVB3-induced VMC remains

국제 무역 품목 번호

SKUGTIN
CBL18604053252409417

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