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Merck

MAB1587

Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2

clone 4D6.2, Chemicon®, from mouse

동의어(들):

EAAT3

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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제품 이름

Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2, clone 4D6.2, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

4D6.2, monoclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SLC1A1(6505)

Application

Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2 is an antibody against Glutamate Transporter for use in IH & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1-2 μg/mL

Immunohistochemistry: 1-2 μg/mL

Optimal working dilutions must be determined by end user.



EAAC1 is approximately 66-70kDa; the protein can form homomultimers during preparation as well, thus often times large 200-220kDa bands can also be seen.

Biochem/physiol Actions

Glutamate Transporter EAAC1.

Based on protein sequence the antibody is expected to react with mouse, bovine and rabbit.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

C-terminus peptide (KDKSDTISFTQTSQF) (Catalog Number AG372).

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl, pH 7.6 with 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C for up to six months.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Clozapine-induced reduction of glutamate transport in the frontal cortex is not mediated by GLAST and EAAC1.
M Melone et al.
Molecular psychiatry, 8(1), 12-13 (2003-01-31)
Bárbara Coimbra et al.
Nature communications, 10(1), 4138-4138 (2019-09-14)
The laterodorsal tegmentum (LDT) is associated with reward considering that it modulates VTA neuronal activity, but recent anatomical evidence shows that the LDT also directly projects to nucleus accumbens (NAc). We show that the majority of LDT-NAc inputs are cholinergic
M C Medrano et al.
British journal of pharmacology, 169(8), 1781-1794 (2013-05-04)
Excitatory amino acid transporters (EAATs) in the CNS contribute to the clearance of glutamate released during neurotransmission. The aim of this study was to explore the role of EAATs in the regulation of locus coeruleus (LC) neurons by glutamate. We
Han-Byeol Kim et al.
Cell death discovery, 6, 73-73 (2020-08-21)
Neonatal maternal separation (NMS), as an early-life stress (ELS), is a risk factor to develop emotional disorders. However, the exact mechanisms remain to be defined. In the present study, we investigated the mechanisms involved in developing emotional disorders caused by
Han-Byeol Kim et al.
Molecular brain, 13(1), 153-153 (2020-11-15)
Excitatory amino acid carrier 1 (EAAC1) is an important subtype of excitatory amino acid transporters (EAATs) and is the route for neuronal cysteine uptake. CoCl2 is not only a hypoxia-mimetic reagent but also an oxidative stress inducer. Here, we found

국제 무역 품목 번호

SKUGTIN
MAB158704053252318764

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