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Merck

GF305

IFN- γ Protein, Human Recombinant Animal Free

The Interferon gamma (or IFN-γ protein) is an acid-labile interferon produced by CD4 & CD8 T lymphocytes as well as activated NK cells. Manufactured using all non-animal reagents.

동의어(들):

IFN, Interferon Gamma, IFNG, IFN Gamma

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352202
NACRES:
NA.77
eCl@ss:
32160405
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제품 이름

IFN- γ Protein, Human Recombinant Animal Free, The Interferon gamma (or IFN-γ protein) is an acid-labile interferon produced by CD4 & CD8 T lymphocytes as well as activated NK cells. Manufactured using all non-animal reagents.

assay

>98% (SDS-PAGE and HPLC)

impurities

<0.1 μg/mg protein endotoxin (<1EU/μg)

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Quality Level

Analysis Note

Bioactivity assay: Determined by its ability to induce apoptosis in HeLa cells. The expected ED50 for this effect is 5.0-10.0 ng/ml.

General description

Interferon gamma (IFN-γ) is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-γ signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulate the antigen-specific phases of the immune response. Additionally, IFN-γ stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-γ species-specific and is biologically active only in human and primate cells. Recombinant human IFN-γ is a 16.7 kDa protein containing 143 amino acid residues.

Physical form

Recombinant animal free human IFN- γ is manufactured using all non-animal reagents

저장 등급

11 - Combustible Solids

wgk

WGK 1


시험 성적서(COA)

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문서 라이브러리 방문

Hong-Lin Luo et al.
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Epithelial-mesenchymal transition (EMT) promotes migration, invasion, and metastasis of hepatocellular carcinoma (HCC) cells. The molecular mechanisms behind EMT and metastasis in HCC remain unclear. Microarray analysis was used to identify lncRNAs expression during polarization of U937 macrophages from M2 to
Rojo A Ratsimandresy et al.
Nature communications, 8, 15556-15556 (2017-06-06)
Inflammasomes are protein platforms linking recognition of microbe, pathogen-associated and damage-associated molecular patterns by cytosolic sensory proteins to caspase-1 activation. Caspase-1 promotes pyroptotic cell death and the maturation and secretion of interleukin (IL)-1β and IL-18, which trigger inflammatory responses to

관련 콘텐츠

New Products: Antibodies, Assays, Small Molecules, Inhibitors, and Proteins

국제 무역 품목 번호

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GF30504053252691461

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