203389 InSolution™Blebbistatin, Racemic - Calbiochem

203389
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      개요

      Replacement Information

      주요 사양표

      Empirical Formula
      C₁₈H₁₆N₂O₂

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      카탈로그 번호 재고 정보패킹 포장 단위 가격(VAT 별도) 수량
      203389-5MGCN
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          Plastic ampoule 5 mg
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          Description
          Catalogue Number203389
          Brand Family Calbiochem®
          References
          ReferencesShu, S., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 1472.
          Kovacs, M., et al. 2004. J. Biol. Chem. 279, 35557.
          Straight, A.F., et al. 2003. Science 299, 1743.
          Cheung, A., et al. 2001. Mol. Biol. Cell Suppl. 12, 271a.
          Product Information
          ATP CompetitiveN
          FormLiquid
          FormulationA 50 mM (5 mg/342 µl) solution of (±)-Blebbistatin (Cat. No. 203390) in 90% DMSO.
          Hill FormulaC₁₈H₁₆N₂O₂
          Chemical formulaC₁₈H₁₆N₂O₂
          Hygroscopic Hygroscopic
          ReversibleY
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          ApplicationInSolution™Blebbistatin, Racemic, is a 50 mM in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis.
          Biological Information
          Primary TargetATPase
          Primary Target IC<sub>50</sub><100 µM inhibiting the ATPase and gliding motility of human platelets
          Purity≥97% by HPLC
          Physicochemical Information
          Cell permeableY
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped with Blue Ice or with Dry Ice
          Toxicity Harmful & Carcinogenic / Teratogenic
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          InSolution™Blebbistatin, Racemic - Calbiochem MSDS

          타이틀

          물질안전보건자료(MSDS) 

          InSolution™Blebbistatin, Racemic - Calbiochem Certificates of Analysis

          TitleLot Number
          203389

          References

          참고문헌 보기
          Shu, S., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 1472.
          Kovacs, M., et al. 2004. J. Biol. Chem. 279, 35557.
          Straight, A.F., et al. 2003. Science 299, 1743.
          Cheung, A., et al. 2001. Mol. Biol. Cell Suppl. 12, 271a.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision20-May-2008 RFH
          DescriptionA cell-permeable compound that acts as a selective, potent, and reversible inhibitor of non-muscle myosin II. Inhibits the ATPase and gliding motility of human platelets (≤100 µM) without affecting myosin light chain kinase (MLCK) activity. Has been shown to block cell blebbing and to rapidly disrupt directed cell migration and cytokinesis in vertebrate cells. Does not disrupt mitosis or affect contractile ring assembly.
          FormLiquid
          FormulationA 50 mM (5 mg/342 µl) solution of (±)-Blebbistatin (Cat. No. 203390) in 90% DMSO.
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₁₈H₁₆N₂O₂
          Structure formulaStructure formula
          Purity≥97% by HPLC
          Storage -20°C
          Hygroscopic
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
          Toxicity Harmful & Carcinogenic / Teratogenic
          ReferencesShu, S., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 1472.
          Kovacs, M., et al. 2004. J. Biol. Chem. 279, 35557.
          Straight, A.F., et al. 2003. Science 299, 1743.
          Cheung, A., et al. 2001. Mol. Biol. Cell Suppl. 12, 271a.