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Merck

1.00681

Succinic acid

crystalline, EMPROVE® ESSENTIAL, ChP, NF, JPE

동의어(들):

Butanedioic acid

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제품정보 (DICE 배송 시 비용 별도)

Linear Formula:
HOOCCH2CH2COOH
CAS 번호:
Molecular Weight:
118.09
EC Index Number:
203-740-4
UNSPSC Code:
12352106
Beilstein/REAXYS Number:
1754069
MDL number:
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Quality Level

agency

ChP, JPE, NF

product line

EMPROVE® ESSENTIAL

assay

99.0-100.5% (HPLC)

form

crystalline, solid

autoignition temp.

470 °C

technique(s)

API processing | cocrystal formation: suitable, API processing | salt formation: suitable

bp

235 °C (lit.), 235 °C/1013 hPa

mp

184-186 °C (lit.)

transition temp

flash point 206 °C

solubility

58 g/L

density

1.56 g/cm3 at 20 °C

anion traces

chloride (Cl-): ≤0.001%, phosphate (PO43-): ≤0.001%, sulfate (SO42-): ≤0.003%

cation traces

As: ≤0.0002%, Fe: ≤5 ppm, heavy metals (as Pb): ≤0.0020%, heavy metals (as Pb): ≤5 ppm

application(s)

liquid formulation
pharma/biopharma processes
pharmaceutical
solid formulation

storage temp.

2-30°C

SMILES string

OC(=O)CCC(O)=O

InChI

1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)

InChI key

KDYFGRWQOYBRFD-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Succinic acid is a commonly used ingredient in pharmaceutical applications. In such applications it has been used primarily for solid oral dosage forms.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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문서

Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.





국제 무역 품목 번호

SKUGTIN
1.00681.500004022536008943
1.00681.905004022536008950