Quality Segment
description
shipped with cooling packs
product line
Cellvento®
form
compacted dry powder
greener alternative product characteristics
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.
sustainability
Sustainability features
technique(s)
cell culture | mammalian: suitable (suspension)
application(s)
pharma/biopharma processes
storage temp.
2-8°C
General description
Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield.The formulation has been specifically designed to provide increased process control and decreased complexity. Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter. As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.
Cellvento® ModiFeed Prime COMP is a highly concentrated, one-part, pH neutral feed added to replenish depleted nutrients required for cellular function and to extend the production phase in fed-batch mode. This single feed is highly concentrated, allowing for a reduction in volume of feed added to the medium thereby increasing product yield. This product is a Design for Sustainability (DfS) developed product.Click here to view its DfS scorecard.
Application
- Cellvento® ModiFeed Prime COMP has been developed as a feed supplement to be used in combination with the production media, Cellvento® 4CHO COMP and EX-CELL® Advanced CHO, during fed-batch manufacturing processes.
- It has been designed to support optimal cell growth and high productivity of suspension CHO cell lines such as CHO-K1, CHO-DG44, CHO-S and CHO-GS, including cell lines derived using the CHOZN® platform Fed-batch (batch, perfusion)
Features and Benefits
- The formulation has been specifically designed to provide increased process control and decreased complexity.
- Exclusion of glucose from the formulation allows for fed-batch process dictated regulation of this critical parameter.
- As a one-part feed, containing modified amino acids and amino acid derivatives, the complexity of hydration, storage, and feeding is drastically reduced.
Preparation Note
Formulated to contain 131.6 grams of powder per liter of medium.
Legal Information
CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany
CHOZN is a registered trademark of Merck KGaA, Darmstadt, Germany
EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
저장 등급
11 - Combustible Solids
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WGK 3
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예:
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제품 번호
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25G
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추가적인 예시:
705578-5MG-PW
PL860-CGA/SHF-1EA
MMYOMAG-74K-13
1000309185
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