ligand
protein A
Quality Segment
form
resin
specific analyte(s)
MAbs
manufacturer/tradename
Eshmuno®
parameter
>500 cm/hr flow rate, 8 bar max. pressure
matrix active group
polymer, polyvinyl ether
mean particle size
50 μm
capacity
40-55 mg/mL binding capacity
transition temp
flash point 35 °C (calculated)
separation technique
affinity
storage temp.
2-8°C
General description
Protein A affinity resin based on polyvinyl ether base matrix
Features and Benefits
Eshmuno® A chromatography resin provides users with:
- An Intensified processes resulting in High Binding Capacity, Superior Flow Capability, and Excellent HCP reduction.
- Products purity with a more consistent viral clearance, increased aggregate removal, reduced fab finding and low leached Protein A
- High dynamic binding capacity at high flow rate
- Aggregate removal, Alkaline Stability and Acid cleaning compatibility
Packaging
- 1.20089.0100: Eshmuno® A Resin 100 ml
- 1.20089.9010: Eshmuno® A Resin 10 L
- 1.20089.0010: Eshmuno® A Resin 10 ml
- 1.20089.0500: Eshmuno® A Resin 500 ml
- 1.20089.5000: Eshmuno® A Resin 5 L
Plastic bottle
Analysis Note
Appearance: Milky turbid suspension, free from coarse mechanical impurities
Microscopic evaluation: Spherical particles, no agglomerates, no fines
Particle size (30 – 70 µm): ≥ 80 %
Endotoxins: ≤ 1.00 EU/ml
TAMC (Total aerobic microbial count): ≤ 100 CFU/ml
TYMC (Total yeast and mould count): ≤ 100 CFU/ml
Capacity (IgG): ≥ 55 mg/ml
Leakage (Protein A): ≤ 100 ppm
Microscopic evaluation: Spherical particles, no agglomerates, no fines
Particle size (30 – 70 µm): ≥ 80 %
Endotoxins: ≤ 1.00 EU/ml
TAMC (Total aerobic microbial count): ≤ 100 CFU/ml
TYMC (Total yeast and mould count): ≤ 100 CFU/ml
Capacity (IgG): ≥ 55 mg/ml
Leakage (Protein A): ≤ 100 ppm
Legal Information
Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany
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signalword
Warning
hcodes
Hazard Classifications
Flam. Liq. 3
저장 등급
3 - Flammable liquids
wgk
WGK 1
flash_point_f
95.0 °F
flash_point_c
35 °C
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