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Merck

251700

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride

UPA inhibitor, solid

동의어(들):

1,5-DNS-GGACK, 2HCl

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352200
NACRES:
NA.77
Form:
solid
Quality level:
Storage condition:
OK to freeze, desiccated
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제품 이름

1,5-Dansyl-Glu-Gly-Arg Chloromethyl Ketone, Dihydrochloride, Effective irreversible inhibitor of uPA, Factor Xa, and urokinase.

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, desiccated

color

off-white

solubility

soluble (Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.)

shipped in

ambient

storage temp.

2-8°C

General description

Effective irreversible inhibitor of uPA, Factor Xa, and urokinase. Fluorophore allows direct monitoring of interactions of labeled enzyme. Does not inhibit tPA.

Biochem/physiol Actions

Cell permeable: no
Primary Target
UPA
Product does not compete with ATP.
Reversible: no
Target IC50: 100 nM for factor Xa

Preparation Note

Following initial thaw, aliquot and refrigerate (4°C). Stock solutions are stable for up to 4 months at 4°C.
Reconstitute at 1 mg/ml in 10 mM HCl. Dilute with physiological buffers just prior to use.

Other Notes

Bajaj, S.P., et al. 1992. Proc. Natl. Acad. Sci. USA89, 152.
Bergmeyer, H.V. 1984. Methods Enzym. Anal. 5, 375.
Kettner, C., and Shaw, E. 1981. Methods Enzymol.80, 826.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


저장 등급

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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국제 무역 품목 번호

SKUGTIN
251700-5MGCN04055977217957