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559276

Ryanodine

≥98% (HPLC), solid, Ca2+ release blocker, Calbiochem®

동의어(들):

Ryanodine, High Purity

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C25H35NO9
CAS 번호:
15662-33-6
Molecular Weight:
493.55
MDL number:
MFCD00151119
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
100
Storage condition:
OK to freeze, protect from light
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제품 이름

Ryanodine, High Purity, Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum.

description

Merck USA index - 14, 8307

Quality Level

100

assay

≥98% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

white

solubility

water: 1 mg/mL, methanol: 20 mg/mL

shipped in

ambient

storage temp.

10-30°C

SMILES string

[nH]1c(ccc1)C(=O)O[C@H]2[C@@]3([C@]4([C@]65O[C@]([C@]4([C@@]2(O)C(C)C)C)(C[C@]3([C@]6(CC[C@@H]([C@H]5O)C)O)C)O)O)O

InChI

1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12-13,15,17,26-27,29-33H,8-9,11H2,1-5H3/t13-,15+,17+,18-,19-,20-,21-,22+,23+,24+,25+/m0/s1

InChI key

JJSYXNQGLHBRRK-YSOSZROBSA-N

General description

Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum. Has many complex effects on Ca2+ transport and action in muscle. Purified from Ryanodine Mixture.

Biochem/physiol Actions

Cell permeable: no
Primary Target
Ca2+ transport and action in muscle
Product does not compete with ATP.
Reversible: no

Preparation Note

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

Other Notes

Sorrentino, V., and Volpe, P. 1993. Trends Pharmacol. Sci.14, 98.
Sabbadini, R., et al. 1992. J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B. 1985. Biochim. Biophys. Acta813, 77.
Marban, E., and Wier, W.G. 1985. Circ. Res.56, 133.
Sukto, J.L., et al. 1985. Fed. Proc.44, 2984.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful (C)

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

저장 등급

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

시험 성적서(COA)

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국제 무역 품목 번호

SKUGTIN
559276-500UGCN04055977192353