PC41
Anti-Cathepsin B (Ab-3) Rabbit pAb
liquid, Calbiochem®
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크기 선택
제품정보 (DICE 배송 시 비용 별도)
NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
human
Application:
Citations:
6
제품 이름
Anti-Cathepsin B (Ab-3) Rabbit pAb, liquid, Calbiochem®
form
liquid
biological source
rabbit
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
contains
≤0.1% sodium azide as preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
do not freeze
dilution
(Immunoblotting (1 µg/mL)
Paraffin Sections (2.5 µg/mL, trypsin pre-treatment required))
isotype
IgG
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Analysis Note
Positive Control
SK-HEP-1 concentrated conditioned medium or breast carcinoma tissue
SK-HEP-1 concentrated conditioned medium or breast carcinoma tissue
Application
Immunoblotting (1 µg/ml)
Paraffin Sections (2.5 µg/ml, trypsin pre-treatment required)
Paraffin Sections (2.5 µg/ml, trypsin pre-treatment required)
Disclaimer
Toxicity: Standard Handling (A)
General description
Anti-Cathepsin B (Ab-3), rabbit polyclonal, recognizes the ~43 kDa latent and ~31 kDa active forms of cathepsin B in breast carcinoma. It is validated for Western blotting and for paraffin sections.
Purified rabbit polyclonal antibody. Recognizes the ~43 kDa latent and the ~31 kDa active forms of cathepsin B.
Recognizes the ~43 kDa latent and the ~31 kDa active forms of cathepsin B in breast carcinoma tissues.
Immunogen
Human
purified human liver cathepsin B
Other Notes
Antibody should be titrated for optimal results in individual systems.
Barrett, A.J. and Kirschke, H. 1981. Methods Enzymol.80, 535.
Chan, S.J., et al. Proc. Natl. Acad. Sci. USA83, 7721.
Barrett, A.J. 1987. Trends Biochem. Sci.12, 193.
Sloane, B.F. 1990. in Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 137.
Chan, S.J., et al. Proc. Natl. Acad. Sci. USA83, 7721.
Barrett, A.J. 1987. Trends Biochem. Sci.12, 193.
Sloane, B.F. 1990. in Seminars in Cancer Biology, ed. M. M. Gottesman. Vol. 1(2), 137.
Packaging
Please refer to vial label for lot-specific concentration.
Physical form
In 0.05 M sodium phosphate buffer, 0.2% gelatin.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Mehrnoosh Saghizadeh et al.
Investigative ophthalmology & visual science, 46(10), 3604-3615 (2005-09-28)
To identify proteinases and growth factors abnormally expressed in human corneas of donors with diabetic retinopathy (DR), additional to previously described matrix metalloproteinase (MMP)-10 and -3 and insulin-like growth factor (IGF)-I. RNA was isolated from 35 normal, diabetic, and DR
Paola Pellegrini et al.
Autophagy, 10(4), 562-571 (2014-02-05)
Acidic pH is an important feature of tumor microenvironment and a major determinant of tumor progression. We reported that cancer cells upregulate autophagy as a survival mechanism to acidic stress. Inhibition of autophagy by administration of chloroquine (CQ) in combination
Wenqian Fang et al.
Translational research : the journal of laboratory and clinical medicine, 222, 28-40 (2020-05-22)
Nonalcoholic steatohepatitis (NASH) is a severe form of nonalcoholic fatty liver disease characterized by fat accumulation and inflammation in liver. Yet, the mechanistic insight and diagnostic and therapeutic options of NASH remain incompletely understood. This study tested the roles of
Yixing Wu et al.
Acta neuropathologica communications, 11(1), 132-132 (2023-08-15)
Cathepsin B is a cysteine protease that is implicated in multiple aspects of Alzheimer's disease pathogenesis. The endogenous inhibitor of this enzyme, cystatin B (CSTB) is encoded on chromosome 21. Thus, individuals who have Down syndrome, a genetic condition caused
Xian Zhang et al.
iScience, 19, 607-622 (2019-08-26)
Transforming growth factor beta (TGF-β) signaling contributes to tissue fibrosis. Here we demonstrate that TGF-β enhances CatS and CatK expression but reduces CatB and CatL expression in mouse kidney tubular epithelial cells (TECs). CatS- and CatK deficiency reduces TEC nuclear
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| PC41-100UGCN | 04055977224597 |
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