제품 이름
Anti-Sodium-Calcium Exchanger 1 Antibody, Chemicon®, from rabbit
biological source
rabbit
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC8A1(6546)
Application
Anti-Sodium-Calcium Exchanger 1 Antibody is an antibody against Sodium-Calcium Exchanger 1 for use in ELISA & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot: 1-10 μg/mL using ECL.
ELISA: 0.5-1 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
ELISA: 0.5-1 μg/mL using 1 μg/mL control peptide per well.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes rat Sodium Calcium Exchanger 1 (NCX1). The immunogen shows no significant sequence homology with other NCX proteins.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
A 23 amino acid peptide sequence within the cytoplasmic domain 3 rat NCX1 (Low et al. 1993; Furman et al. 1993; Lee et al. 1994; Nicoll et al. 1996; Kumoro et al. 1992; Blaustein & Lederer 1999).
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Affinity purified immunoglobulin. Liquid in PBS containing 0.1% BSA.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia.
Chen, L; Zhang, J; Hu, X; Philipson, KD; Scharf, SM
Journal of Applied Physiology (1985)
Vijayababu M Radhakrishnan et al.
The Journal of biological chemistry, 290(14), 8964-8974 (2015-02-05)
NCX1 is a Na(+)/Ca(2+) exchanger, which is believed to provide a key route for basolateral Ca(2+) efflux in the renal epithelia, thus contributing to renal Ca(2+) reabsorption. Altered mineral homeostasis, including intestinal and renal Ca(2+) transport may represent a significant
Xuehui Wang et al.
Frontiers in pharmacology, 10, 616-616 (2019-07-10)
Background: Neuregulin (NRG-1), an essential stress-mediated paracrine growth factor, has a cardioprotective effect in failing heart. However, the underlying mechanism remains unclear. The role of NRG-1β in heart failure (HF) rats was examined. Methods and Results: Volume-overload HF rat model
Sharlene M Day et al.
Physiological genomics, 33(3), 312-322 (2008-03-13)
Relaxation abnormalities are prevalent in heart failure and contribute to clinical outcomes. Disruption of Ca2+ homeostasis in heart failure delays relaxation by prolonging the intracellular Ca2+ transient. We sought to speed cardiac relaxation in vivo by cardiac-directed transgene expression of
Douglas E Brenneman et al.
Journal of molecular neuroscience : MN, 68(4), 603-619 (2019-05-12)
Treatment with cannabidiol (CBD) or KLS-13019 (novel CBD analog), has previously been shown to prevent paclitaxel-induced mechanical allodynia in a mouse model of chemotherapy-induced peripheral neuropathy (CIPN). The mechanism of action for CBD- and KLS-13019-mediated protection now has been explored
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| AB3516P | 04053252740145 |
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