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Merck

AB5804

Anti-Glial Fibrillary Acidic Protein Antibody

CHEMICON®, rabbit polyclonal

동의어(들):

glial fibrillary acidic protein

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
기술 서비스
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제품 이름

Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody, serum, Chemicon®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, bovine, canine, rat

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... GFAP(2670)

Analysis Note

Control
Mouse brain tissue, rat astrocytes, rat neurons.
Routinely evaluated by immunohistochemistry on brain tissue, astrocytes, and neurons.

Immunohistochemistry(paraffin) Analysis:
GFAP (IHC2078) staining of Human Brain. Tissue pretreated with Citrate Buffer, pH 6.0. Pre-diluted polyclonal antibody, using IHC-Select Detection with HRP-DAB. Glial cells stain strongly (brown).
Optimal Staining with Citrate Buffer Epitope Retrieval: Human Brain

Application

Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody is an antibody against Glial Fibrillary Acidic Protein (GFAP) for use in IC, IH, IH(P) with more than 65 product citations.
Immunohistochemistry(paraffin):
Representative images from a previous lot.

Immunocytochemistry:
A 1:1,000 dilution of a previous lot was used in Immunocytochemistry.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Biochem/physiol Actions

It is expected that the antibody will react with most mammalian GFAP due to homology. Reactivity with other species has not been confirmed.
Recognizes Glial Fibrillary Acidic Protein (GFAP).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

50 kDa
Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.

Immunogen

Purified bovine GFAP

Physical form

Rabbit serum. Liquid. Contains no preservative.
Unpurified

Preparation Note

Stable for 1 year at -20°C undiluted aliquots from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Diego Mastroeni et al.
PloS one, 4(8), e6617-e6617 (2009-08-13)
DNA methylation is capable of modulating coordinate expression of large numbers of genes across many different pathways, and may therefore warrant investigation for their potential role between genes and disease phenotype. In a rare set of monozygotic twins discordant for
Congenital anomalies and rhabdoid tumor associated with 22q11 germline deletion and somatic inactivation of the SMARCB1 tumor suppressor.
Toth, G; Zraly, CB; Thomson, TL; Jones, C; Lapetino, S; Muraskas, J; Zhang, J; Dingwall, AK
Genes Chromosomes Cancer null
Antonio Currais et al.
Aging cell, 11(6), 1017-1026 (2012-09-04)
Mounting evidence supports a link between diabetes, cognitive dysfunction, and aging. However, the physiological mechanisms by which diabetes impacts brain function and cognition are not fully understood. To determine how diabetes contributes to cognitive dysfunction and age-associated pathology, we used
A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system.
Wagner, N; Wagner, KD; Hammes, A; Kirschner, KM; Vidal, VP; Schedl, A; Scholz, H
Development null
Intracranial V. cholerae sialidase protects against excitotoxic neurodegeneration.
Dhanushkodi, A; McDonald, MP
Testing null

문서

ReNcell neural progenitors are immortalized human neural stem cell lines that can differentiate into neurons, astrocytes sand oligodendrocytes.

프로토콜

Step-by-step culture protocols for neural stem cell culture including NSC isolation, expansion, differentiation and characterization.

관련 콘텐츠

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

국제 무역 품목 번호

SKUGTIN
AB580408436037125355

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