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Merck

MAB1273A4

Anti-Mitochondria Antibody, clone 113-1, Alexa Fluor 488 conjugate

clone 113-1, from mouse, ALEXA FLUOR 488

동의어(들):

Human Mitochondria

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
ALEXA FLUOR 488
Clone:
113-1, monoclonal
Application:
immunocytochemistry
Species reactivity:
human (mitochondria protein)
Citations:
8
Technique(s):
immunocytochemistry: suitable
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제품 이름

Anti-Mitochondria Antibody, clone 113-1, Alexa Fluor 488 conjugate, clone 113-1, from mouse, ALEXA FLUOR 488

biological source

mouse

conjugate

ALEXA FLUOR 488

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

113-1, monoclonal

species reactivity

human (mitochondria protein)

should not react with

mouse (mitochondria protein), rat (mitochondria protein)

technique(s)

immunocytochemistry: suitable

isotype

IgG1

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Legal Information

ALEXA FLUOR is a trademark of Life Technologies

Analysis Note

Evaluated by Immunocytochemistry in human adipose mesenchymal stem cells (SCC038).
Immunocytochemsitry Analysis: A 1:50 dilution of this antibody detected mitrochondria in human adipose mesenchymal stem cells (SCC038).

Application

Detect Mitochondrial Marker using this mouse monoclonal antibody, Anti-Mitochondria Antibody, clone 113-1 & Alexa Fluor 488 conjugate validated for use in ICC.
Evaluated by Immunocytochemistry in primary mouse embryonic fibroblasts (PMEFs).
Immunocytochemsitry Analysis: A 1:50 dilution of this antibody did not detect mitrochondria in primary mouse embryonic fibroblasts (PMEFs).

General description

60 kDa calculated
This antibody recognizes a 60 kDa nonglycosylated protein component of mitochondria found in human cells. It can be used to stain mitochondria in cell, tissue or biochemical preparations and can be used as a marker of the mitochondria in subcellular fractions. MAB1273A4 recognizes a 65 kD protein by immunoprecipitation and produces the stringy, "spaghetti-like", staining patten in the cytoplasm of human cells.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Anna C Krieger et al.
Cancers, 15(10) (2023-06-22)
Cardiolipin (CL) is a mitochondrial lipid with diverse roles in cellular respiration, signaling, and organelle membrane structure. CL content and composition are essential for proper mitochondrial function. Deranged mitochondrial energy production and signaling are key components of glial cell cancers
Markus Pasztorek et al.
Frontiers in bioengineering and biotechnology, 7, 338-338 (2019-12-06)
The mechanobiological behavior of mesenchymal stem cells (MSCs) in two- (2D) or three-dimensional (3D) cultures relies on the formation of actin filaments which occur as stress fibers and depends on mitochondrial dynamics involving vimentin intermediate filaments. Here we investigate whether
Hao Chen et al.
Research (Washington, D.C.), 2021, 9798580-9798580 (2021-07-13)
Stem cell therapy holds high promises in regenerative medicine. The major challenge of clinical translation is to precisely and quantitatively evaluate the in vivo cell distribution, migration, and engraftment, which cannot be easily achieved by current techniques. To address this
Jialing Zhang et al.
Cancer research, 76(22), 6588-6597 (2016-11-05)
Oncocytic tumors are characterized by an excessive eosinophilic, granular cytoplasm due to aberrant accumulation of mitochondria. Mutations in mitochondrial DNA occur in oncocytic thyroid tumors, but there is no information about their lipid composition, which might reveal candidate theranostic molecules.
Estelle Porret et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 182, 141-151 (2022-12-19)
Glioblastoma (GBM) is the most common and deadly form of primary brain tumor. Between 30 % and 60 % of GBM are characterized by overexpression of the Epidermal Growth Factor Receptor (EGFR). The anti-EGFR antibody Cetuximab (CTX) showed a favorable effect for

국제 무역 품목 번호

SKUGTIN
MAB1273A404053252918315

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