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Merck

MAB1430

Anti-Collagen Type IV Antibody, clone 24.12.8 (PHM-12)

clone 24.12.8 (PHM-12), Chemicon®, from mouse

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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제품 이름

Anti-Collagen Type IV Antibody, clone 24.12.8 (PHM-12), clone 24.12.8 (PHM-12), Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

clone

24.12.8 (PHM-12), monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Application

Detect Collagen Type IV using this Anti-Collagen Type IV Antibody, clone 24.12.8 (PHM-12) validated for use in IH, IH(P).
The antibody is suitable for use on both frozen and protease digested paraffin processed tissue.

SUGGESTED USAGE

Indirect immunoperoxidase staining - the final dilution will depend on the assay conditions and detection system employed. However, a dilution of at least 1:40 will be applicable to most commonly used systems.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

MAB1430 provides a marker for an antigen known to be important in glomerular cell-matrix interactions, and should prove useful in research into the mechanisms involved in renal pathology. This antibody reacts with glomerular and tubular basement membranes in kidney as well as basal lamina of capillaries. It also labels mesangial cells and matrix within the glomerulus as well as basement membrane structures in all organs examined (Gusterson et al., 1984).

General description

BIOCHEMISTRY:

p I = 5.5

Immunogen

Human glomeruli

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Purified immunoglobulin presented as a liquid in phosphate buffered saline, pH 7.4, containing 0.2% bovine serum albumin and 0.1% sodium azide.

Preparation Note

Store at 2 to 8°C, for up to 6 months. For prolonged periods, store below -20°C in undiluted aliquots. AVOID REPEATED FREEZE/THAW CYCLES.

WARNING: The monoclonal reagent solution contains 0.1% sodium azide as a preservative. Due to potential hazards arising from the build up of this material in pipes, spent reagent should be disposed of with liberal volumes of water.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

저장 등급

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Fibroblasts facilitate re-epithelialization in wounded human skin equivalents.
El Ghalbzouri, Abdoelwaheb, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 84, 102-112 (2004)
Functional characterization of cancer-associated fibroblasts of human cutaneous squamous cell carcinoma.
Suzan Commandeur,Suet Huy Ho,Frank R de Gruijl,Rein Willemze,Cornelis P Tensen et al.
Experimental Dermatology null
Invading squamous cell carcinoma can retain a basal lamina. An immunohistochemical study using a monoclonal antibody to type IV collagen.
Gusterson, B A, et al.
Laboratory Investigation; a Journal of Technical Methods and Pathology, 51, 82-87 (1984)
Morphofunctional studies of the glomerular wall in mice lacking entactin-1.
Simon-Philippe Lebel, Yong Chen, Diane Gingras, Albert E Chung, Moise Bendayan
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society null
S E Aggrey et al.
Poultry science, 73(12), 1822-1828 (1994-12-01)
Records of 1,530 Japanese quail were used to estimate heritabilities and genetic correlations based on a derivative-free restricted maximum likelihood (REML) method with an animal model and ANOVA. The animal model included fixed effects of hatch and sex, random effects

국제 무역 품목 번호

SKUGTIN
MAB143004053252666605

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