MAB1961
Anti-Integrin αVβ5 Antibody
CHEMICON®, mouse monoclonal, P1F6
동의어(들):
Anti-CD51, Anti-MSK8, Anti-VNRA, Anti-VTNR
조직 및 계약 가격을 보려면 로그인를 클릭합니다.
크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
제품 이름
Anti-Integrin αVβ5 Antibody, clone P1F6, clone P1F6, Chemicon®, from mouse
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
P1F6, monoclonal
species reactivity
human, chicken
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
isotype
IgG1
suitability
not suitable for immunohistochemistry (Paraffin)
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGAV(3685)
Analysis Note
Control
Epithelium, keratinocytes
Epithelium, keratinocytes
Application
Inhibition of attachment of HT29 cells to vitronectin: >1:1,000
Inhibition of attachment of carcinoma and melanoma cells to vitronectin.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue. (Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.)
Immunocytochemistry: 1:1500. For use on human carcinomas, normal epithelium and keratinocytes (Acetone Fixed Only).
Immunoprecipitation
FACS
EIA
Optimal working dilutions must be determined by the end user.
Inhibition of attachment of carcinoma and melanoma cells to vitronectin.
Immunohistochemistry: for use on acetone or paraformaldehyde fixed tissue. (Staining of formalin-fixed tissues REQUIRES boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min.)
Immunocytochemistry: 1:1500. For use on human carcinomas, normal epithelium and keratinocytes (Acetone Fixed Only).
Immunoprecipitation
FACS
EIA
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
This Anti-Integrin αVβ5 Antibody, clone P1F6 is validated for use in FC, IC, IH, IP, FUNC for the detection of Integrin αVβ5.
Biochem/physiol Actions
Reacts with the human integrin alphaVbeta5.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha V chain. Alpha chain V undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Immunogen
Human UCLA P3 cells (lung carcinoma)
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
Protein A purified
Preparation Note
Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro.
Aldrian, S; Trautinger, F; Frohlich, I; Berger, W; Micksche, M; Kindas-Mugge, I
Cell Stress & Chaperones null
Endocytosis and nuclear trafficking of adeno-associated virus type 2 are controlled by rac1 and phosphatidylinositol-3 kinase activation.
Sanlioglu, S; Benson, PK; Yang, J; Atkinson, EM; Reynolds, T; Engelhardt, JF
Journal of virology null
The differentiation of pancreatic tumor-initiating cells by vitronectin can be blocked by cilengitide.
Cabarcas, SM; Sun, L; Mathews, L; Thomas, S; Zhang, X; Farrar, WL
Pancreas null
Ba Reun Kim et al.
Biochimica et biophysica acta, 1842(9), 1324-1332 (2014-05-20)
Periostin, an extracellular matrix protein, is expressed in injured tissues, such as the heart with myocardial infarction, and promotes angiogenesis and tissue repair. However, the molecular mechanism associated with periostin-stimulated angiogenesis and tissue repair is still unclear. In order to
Increased adenovirus Type 5 mediated transgene expression due to RhoB down-regulation.
Majhen, D; Stojanovic, N; Vukic, D; Pichon, C; Leduc, C; Osmak, M; Ambriovic-Ristov, A
Testing null
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| MAB1961 | 04053252361128 |
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