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Merck

MAB2052

Anti-Disialoganglioside GD2 Antibody, clone 14G2a

clone 14.2Ga, Chemicon®, from mouse

동의어(들):

Anti-GD2 Antibody, Clone 14G2a Anti-GD2, GD2 Detection Antibody

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제품정보 (DICE 배송 시 비용 별도)

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
14.2Ga, monoclonal
Species reactivity:
human
Application:
flow cytometry
immunofluorescence
immunohistochemistry
Technique(s):
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
Citations:
10
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제품 이름

Anti-Disialoganglioside GD2 Antibody, clone 14G2a, clone 14.2Ga, Chemicon®, from mouse

biological source

mouse

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

14.2Ga, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

isotype

IgG2a

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

관련 카테고리

Application

Anti-Disialoganglioside GD2 Antibody, clone 14G2a detects level of Disialoganglioside GD2 & has been published & validated for use in FC, IF, IH.
Immunohistochemistry (frozen tissue sections)(Cheresh et al., 1986)

Immunofluorescence of cells in culture

Flow cytometry: 1-2 μg per 10E6 cells

Cytotoxicity for GD2 positive cells (Mujoo et al., 1987, 1989)

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts specifically with human GD2 ganglioside.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Cell culture supernatant in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.1% Sodium Azide
Format: Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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저장 등급

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


시험 성적서(COA)

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이 제품을 이미 가지고 계십니까?

문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Patrizia Garbati et al.
International journal of molecular sciences, 22(13) (2021-07-03)
High-risk neuroblastoma (HR-NB) still remains the most dangerous tumor in early childhood. For this reason, the identification of new therapeutic approaches is of fundamental importance. Recently, we combined the conventional pharmacological approach to NB, represented by cisplatin, with fendiline hydrochloride
Christian M Seitz et al.
Oncoimmunology, 9(1), 1683345-1683345 (2020-02-01)
Expression of the disialoganglioside GD2 has been identified as a marker antigen associated with a breast cancer stem-like cell (BCSC) phenotype. Here, we report on the evaluation of GD2 as a BCSC-specific target antigen for immunotherapy. GD2 expression was confirmed
Antonella Brizzolara et al.
Molecules (Basel, Switzerland), 25(22) (2020-11-14)
Despite significant improvement of neuroblastoma (NB) patients' survival due to recent treatment advancements in recent years, NB is still associated with high mortality rate. In search of novel strategies to increase NB's susceptibility to pharmacological treatments, we investigated the in
Martin V Kolev et al.
Journal of immunology (Baltimore, Md. : 1950), 184(11), 6035-6042 (2010-04-28)
Tumor cells escape clearance by complement by abundantly expressing CD59 and other membrane complement regulators. Recently, we designed a peptide derived from the neural-restrictive silencer factor (REST), REST68, which we showed to inhibit expression of CD59 in tumors lacking the
Patrizia Garbati et al.
Biomedicines, 8(11) (2020-11-07)
To overcome the lack of effective pharmacological treatments for high-risk neuroblastoma (HR-NB), the development of novel in vitro and in vivo models that better recapitulate the disease is required. Here, we used an in vitro multiclonal cell model encompassing NB

국제 무역 품목 번호

SKUGTIN
MAB205204053252615207

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