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크기 선택
제품정보 (DICE 배송 시 비용 별도)
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8G9.2, monoclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
mouse, rat
Citations:
123
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
제품 이름
Anti-Vesicular Glutamate Transporter 2 Antibody, clone 8G9.2, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
8G9.2, monoclonal
species reactivity
mouse, rat
species reactivity (predicted by homology)
human
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SLC17A6(57084)
Analysis Note
Evaluated by Western Blot on Mouse brain lysates.
Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates.
Western Blotting Analysis: 1:500 dilution of this antibody detected VGLUT2 on 10 µg of Mouse brain lysates.
Application
Detect Vesicular Glutamate Transporter 2 using this Anti-Vesicular Glutamate Transporter 2 Antibody validated for use in WB, IH.
Immunohistochemistry: A 1:50-1:300 dilution of a previous lot worked using ABC with NiDAB on floating mouse brain sections.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
Reacts with VGLUT2 (Vesicular Glutamate Transporter 2).
General description
Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.
56 kDa
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Mouse monoclonal in PBS containing 0.1% sodium azide.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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저장 등급
10 - Combustible liquids
wgk
WGK 2
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
I Pose et al.
Neuroscience, 172, 246-255 (2010-11-04)
The rostral ventro-medial medullary reticular formation is a complex structure that is involved with a variety of motor functions. It contains glycinergic neurons that are activated during active (rapid eye movement (REM)) sleep (AS); these neurons appear to be responsible
Chia-Chi Liao et al.
The Journal of comparative neurology, 524(7), 1494-1526 (2015-11-01)
A complete unilateral lesion of the dorsal column somatosensory pathway in the upper cervical spinal cord deactivates neurons in the hand region in contralateral somatosensory cortex (areas 3b and 1). Over weeks to months of recovery, parts of the hand
Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum.
Ebner, BA; Ingram, MA; Barnes, JA; Duvick, LA; Frisch, JL; Clark, HB; Zoghbi, HY; Ebner, TJ; Orr, HT
The Journal of Neuroscience null
SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.
Duvick, L; Barnes, J; Ebner, B; Agrawal, S; Andresen, M; Lim, J; Giesler, GJ; Zoghbi, HY; Orr, HT
Neuron null
Austin Ferro et al.
PloS one, 13(7), e0200013-e0200013 (2018-07-06)
Spinocerebellar Ataxia type 1 (SCA1) is a fatal neurodegenerative genetic disease that is characterized by pronounced neuronal loss and gliosis in the cerebellum. We have previously demonstrated microglial activation, measured as an increase in microglial density in cerebellar cortex and
문서
Human iPSC neural differentiation media and protocols used to generate neural stem cells, neurons and glial cell types.
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| MAB5504 | 04053252397523 |
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