제품 이름
Anti-mouse CD44 (H-CAM) Antibody, clone KM201, clone KM201, from rat
biological source
rat
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
KM201, monoclonal
species reactivity
mouse
technique(s)
flow cytometry: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CD44(960)
관련 카테고리
Analysis Note
Control
Mouse bone marrow cells
Mouse bone marrow cells
Evaluated by Flow Cytometry in mouse bone marrow cells.
Flow Cytometry Analysis: 0.1 µg of this antibody detected CD44 in mouse bone marrow cells.
Flow Cytometry Analysis: 0.1 µg of this antibody detected CD44 in mouse bone marrow cells.
Application
Detect mouse CD44 (H-CAM) using this Anti-mouse CD44 (H-CAM) Antibody, clone KM201 validated for use in FC.
Research Category
Cell Structure
Stem Cell Research
Cell Structure
Stem Cell Research
Research Sub Category
Adhesion (CAMs)
Hematopoietic Stem Cells
Adhesion (CAMs)
Hematopoietic Stem Cells
Biochem/physiol Actions
The antibody recognizes CD44 near the hyaluronate binding domain.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
86 kDa calculated
CD44, also known as H-CAM is a distinct adhesion molecule that, with its 13 known isoforms, comprises a family of transmembrane glycoproteins involved in a wide variety of significant biological processes. Members belonging to this family are involved in apoptosis, migration, metastasis, tumor progression, lymphocyte homing, and the attachment of hematopoietic cells to stromal cells. CD44 is the primary cell surface receptor for hyaluronic acid (HA), and is also a notable target for WNT signaling within the intestinal mucosa. Recent studies have used CD44 marker as a means to isolate different cancer stem cells (CSC) such as; colorectal CSC, pancreatic CSC, and prostate CSC.
Immunogen
Epitope: Near the hyaluronate binding domain
Mouse bone marrow-derived stromal cells
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: CBL1308
Physical form
Format: Purified
Protein G
Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine, pH 7.4, 150 mM NaCl, with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
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저장 등급
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Giuseppe M Campo et al.
Innate immunity, 19(5), 462-478 (2013-01-04)
Investigations have suggested degradation of native hyaluronan (HA) into small oligosaccharides as being involved in the development and progression of inflammatory diseases, particularly rheumatoid arthritis (RA). Inflammatory responses occur by modulating the TLR4 and 2, and the CD44 natural HA
Monserrat Gerardo-Ramírez et al.
Cells, 12(9) (2023-05-13)
Primary liver cancer is the third leading cause of cancer-related death worldwide. An increasing body of evidence suggests that the Hippo tumor suppressor pathway plays a critical role in restricting cell proliferation and determining cell fate during physiological and pathological
국제 무역 품목 번호
| SKU | GTIN |
|---|---|
| MABT78 | 04053252746642 |
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