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• Application Note: Rhodium and Palladium Metal Scavenging with Carboxen^® Synthetic Carbon Adsorbents

  The ICH-Q3D-R2 guidelines on permissible elemental impurity levels in drug products require a metal scavenging clean-up step for many active pharmaceutical ingredients (APIs). Organometallic catalysts based on palladium and rhodium are commonly used as process catalysts for the synthesis of APIs. These metals fall under Class-2B of the ICH-Q3D-R2 guidelines, with an oral consumption limit of 10 ppm.

• Application Note: Surface Chemistry of Synthetic Carbon Adsorbents and their Application in the Adsorption of Amines

  Activated carbons are widely used for purification and separation applications, such as purification of permanent gases, removal of volatile organic compounds from streams of gases and liquids, hydrocarbon vapor recovery, purification of active pharmaceutical ingredients, and preparing electrode materials in energy storage devices.

• Application Note: Carboxen^® Synthetic Carbon Adsorbents for Host Cell Protein Removal During Monoclonal Antibody Purification

  The demand for mAbs is steadily increasing while the depletion of host cell proteins (HCP) in the manufacturing of mAbs remains a challenge. HCPs can represent an immune response risk after the administration of mAbs if not reduced to appropriate levels.

• White Paper: Carboxen^® Synthetic Carbon Adsorbents for Industrial Water Purification

  This paper summarizes a selection of field studies that utilized Carboxen^® 563 Synthetic Carbon for the purification of chemical wastewater and contaminated groundwater.

• Brochure: Specialty Carbon Adsorbents Advanced Materials for Industrial Purifications and Separations

  Our specialty carbon adsorbents are highly engineered materials, manufactured from highly pure synthetic polymers. These products are then activated by physical means, avoiding the use of chemicals to activate. This differentiates them from common non-specific, low-tech carbon black and activated carbon adsorbents.

• Brochure: Resins Selection Guide

  Low pressure liquid chromatography (LPLC) is the oldest of chromatographic techniques, originally performed with open columns that use gravity to move the sample through the packing bed. Now, pumps and other instrumentation have been incorporated into LPLC and superior packing media have been developed specifically for this versatile technology.