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Merck

122262

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine

98%

Sinónimos:

Edetol, Entprol, (Ethylenedinitrilo)tetra-2-propanol, Quadrol®

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Acerca de este artículo

Fórmula lineal:
[CH3CH(OH)CH2]2NCH2CH2N[CH2CH(OH)CH3]2
Número CAS:
Peso molecular:
292.41
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
203-041-4
Beilstein/REAXYS Number:
1781143
MDL number:
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Nombre del producto

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine, 98%

InChI key

NSOXQYCFHDMMGV-UHFFFAOYSA-N

InChI

1S/C14H32N2O4/c1-11(17)7-15(8-12(2)18)5-6-16(9-13(3)19)10-14(4)20/h11-14,17-20H,5-10H2,1-4H3

SMILES string

CC(O)CN(CCN(CC(C)O)CC(C)O)CC(C)O

vapor pressure

1 mmHg ( 20 °C)

assay

98%

refractive index

n20/D 1.4812 (lit.)

bp

175-181 °C/0.8 mmHg (lit.)

density

1.013 g/mL at 25 °C (lit.)

Quality Level

Application

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine can be used as:
  • A monomer in the synthesis of covalently cross-linked and amorphous shape memory polyurethane (SMPU) foams that are used in biomedical applications, which includes SMPU actuators for treating ischemic stroke, thrombus removal activated by laser light, self-deployable SMP neuronal electrodes, vascular stents, sutures in microsurgery, ocular implants, bandages, cell manipulation, and cell therapy.
  • A precursor in the preparation of self-healing CFRPs (carbon fiber reinforced polymer) which are thermally responsive with excellent mechanical properties.
  • A crosslinking agent to create a hydrogel that is biocompatible and supports the growth of neural cells. Hydrogels are specifically designed to mimic the properties of the extracellular matrix (ECM), in promoting cell proliferation. The purpose of the hydrogel in this context is to act as an extracellular matrix (ECM) substitute, providing a supportive environment for cell growth and guiding cell adhesion and outgrowth. This study investigates the potential of the peptide-modified channels to facilitate neural tissue engineering and enhance cell proliferation within the hydrogel-based scaffold.

General description

N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine (also known as Quadrol) is an ethylenediamine based monomer used in the production of polyurethane coatings, adhesives, cosmetics and personal care products. It can act as a chelating agent, due to the presence of its four hydroxyl groups, and a crosslinking agent, due to its two amino groups. It is widely used as a building block for polymers and copolymers, particularly those that are designed for use in UV-cross linkable polyurethane polymers, dendritic amino polymers, conducting polymers, inks, and coatings. Additionally, Quadrol is used in the production of resins, as well as in the manufacture of surfactants, plasticizers, and other chemical products.

Legal Information

Quadrol is a registered trademark of BASF Corporation

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

411.8 °F - closed cup

flash_point_c

211 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves


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Thermally responsive self-healing composites with continuous carbon fiber reinforcement
Yunseon Heo and Henry A. Sodano
Composites Science and Technology, 118, 244-250 (2015)
Low density biodegradable shape memory polyurethane foams for embolic biomedical applications
Pooja S, et al.
Acta Biomaterialia, 10(1), 67-76 (2014)
Michael Orlich et al.
Histology and histopathology, 33(2), 181-199 (2017-05-13)
The understanding of spatially complex biological systems is greatly aided by the availability of high resolution information on their tissue architecture, as is provided by optical sectioning microscopy like confocal and light sheet microscopy. In addition, genetically encoded fluorescent reporter
Ona Gyliene et al.
Journal of hazardous materials, 171(1-3), 133-139 (2009-06-23)
The sorption by chitosan in Cu(II) solutions containing tartrate, glycine (amino acetic acid) and quadrol (N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine) as ligands has been investigated. The degree of sorbate removal strongly depends on pH. In solutions containing tartrate almost complete sorption of both Cu(II)
G S Begg et al.
Analytical biochemistry, 138(1), 30-33 (1984-04-01)
Treatment of Quadrol buffer with isothiocyanatophenylthiocarbamylaminoethylaminopropyl glass (DITC glass) substantially reduces the impurities observed when this buffer is used with the spinning cup sequenator. Use of DITC glass-treated Quadrol buffer permits identification of PTH-amino acids from protein degradations down to

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