485926
Sodium L-lactate-13C3 solution
45-55 % (w/w) in H2O, ≥99 atom % 13C, ≥98% (CP), ≥98% (Chiral purity, HPLC)
Sinónimos:
L-Lactic acid-13C3 sodium salt solution
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Fórmula lineal:
13CH313CH(OH)13CO2Na
Número CAS:
Peso molecular:
115.04
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Isotopic purity:
≥99 atom % 13C
Assay:
≥98% (CP), ≥98% (Chiral purity, HPLC)
Mass shift:
M+3
Servicio técnico
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Permítanos ayudarledescription
Packaged as gram of solution 45-55%(w/w)
Quality Level
isotopic purity
≥99 atom % 13C
assay
≥98% (CP), ≥98% (Chiral purity, HPLC)
concentration
45-55 % (w/w) in H2O
technique(s)
mass spectrometry (MS): suitable
mp
163-165 °C (lit.)
mass shift
M+3
storage temp.
−20°C
SMILES string
[Na+].[13CH3][13C@H](O)[13C]([O-])=O
InChI
1S/C3H6O3.Na/c1-2(4)3(5)6;/h2,4H,1H3,(H,5,6);/q;+1/p-1/t2-;/m0./s1/i1+1,2+1,3+1;
InChI key
NGSFWBMYFKHRBD-USULVYIHSA-M
General description
Sodium L-lactate-13C3 is an isotopic analogue of sodium L-lactate.
Application
Sodium L-lactate-13C3 can be used an internal standard for the quantitative determination of blood lactate and pyruvate using filter-paper dried blood spots followed by LC-MS/MS. It can also be used to study the metabolism of NAD redox metabolism or lactate levels, which may be help to develop novel immunotherapies in cancer and therapeutic immunosuppression.
Sodium L-lactate-13C3 has been used as an internal standard in the quantification of metabolites in murine tumor interstitial fluid using the LC/MS technique.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Isolation and Quantification of Metabolite Levels in Murine Tumor Interstitial Fluid by LC/MS
Sullivan MR, et al.
Bio-protocol, 9, e3427-e3427 (2019)
Jin-Wen Song et al.
Cell metabolism, 32(2), 188-202 (2020-07-02)
The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented threat to global public health. Herein, we utilized a combination of targeted and untargeted tandem mass spectrometry to analyze the plasma lipidome and metabolome in mild, moderate, and severe COVID-19 patients
Chih-Kuang Chuang et al.
Journal of chromatography. A, 1216(51), 8947-8952 (2009-11-17)
Lactic acidemia is commonly associated with severe diseases in pediatric patients. Quantitation of blood lactate and pyruvate is important for the diagnosis and clinical management. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method using dried blood spots (DBS) was developed and