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Merck

490024

L-Glutamine-(amide-15N)

98 atom % 15N

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Fórmula lineal:
H215NCO(CH2)2CH(NH2)CO2H
Número CAS:
Peso molecular:
147.14
NACRES:
NA.12
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Isotopic purity:
98 atom % 15N
Assay:
99% (CP)
Mass shift:
M+1
Form:
solid
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isotopic purity

98 atom % 15N

Quality Level

assay

99% (CP)

form

solid

optical activity

[α]25/D +33.0°, c = 2 in 5 M HCl

mp

185 °C (dec.) (lit.)

mass shift

M+1

SMILES string

N[C@@H](CCC([15NH2])=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1/i7+1

InChI key

ZDXPYRJPNDTMRX-QQKKVIQDSA-N

General description

L-Glutamine is a branched chain, non-essential amino acid. It is one of the most abundant amino acid found in central nervous system (CNS), plasma and human skeletal muscle.(2) L- Glutamine is synthesized by transamination of glutamate catalyzed by glutamine synthetase.

Biochem/physiol Actions

L-Glutamine, a source of nitrogen, mainly contributes to the synthesis of proteins, peptides, purine, pyrimidine, nucleotides, nucleic acids and major precursor of neurotransmitter. It acts as a fuel for the proliferation of lymphocytes and macrophages of immune system, for intestinal tissue to maintain gut integrity and for insulin production.(4)(3) L-Glutamine is released by skeletal muscle during stress conditions.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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The influence of oral L-glutamine supplementation on muscle strength recovery and soreness following unilateral knee extension eccentric exercise
Legault Z, et al.
International Journal of Sport Nutrition and Exercise Metabolism, 25(5), 417-426 null
Glutamine and glutamate as vital metabolites
Newsholme P, et al.
Brazilian journal of medical and biological research, 36(2), 153-163 (2003)
Katarzyna Dąbrowska et al.
Neurochemistry international, 118, 225-232 (2018-07-19)
SN1, a system N amino acid transporter specific for astrocytes, is mainly responsible for export of newly synthesized L-glutamine from the cells. Astrocytic retention of L-glutamine which plays a critical role in ammonia-induced astrocytic swelling resulting in brain edema, could