P45850
Pipecolinic acid
98%, for peptide synthesis
Sinónimos:
(±)-Piperidine-2-carboxylic acid, 2-Piperidinecarboxylic acid, Homoproline, Pipecolic acid free base
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Fórmula empírica (notación de Hill):
C6H11NO2
Número CAS:
Peso molecular:
129.16
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
208-616-3
MDL number:
Beilstein/REAXYS Number:
81095
Servicio técnico
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Permítanos ayudarleNombre del producto
Pipecolinic acid, 98%
Quality Level
assay
98%
form
powder and chunks
reaction suitability
reaction type: solution phase peptide synthesis
technique(s)
LC/MS: suitable
color
white to beige
mp
282 °C (dec.) (lit.)
SMILES string
OC(=O)C1CCCCN1
InChI
1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)
InChI key
HXEACLLIILLPRG-UHFFFAOYSA-N
General description
Pipecolinic acid also known as 2-piperidinecarboxylic acid, is a versatile reagent used in the solution phase peptide synthesis. It has been commonly utilized as a replacement for proline in many peptidomimetic syntheses.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Conformational heterogeneity about pipecolic acid peptide bonds: conformational, thermodynamic, and kinetic aspects
WJ Wu
The Journal of Organic Chemistry, 63, 6689-6698 (1998)
D M Danks et al.
The Journal of pediatrics, 86(3), 382-387 (1975-03-01)
Studies of eight patients with this syndrome confirm the characteristic pattern of abnormalities and the autosomal recessive mode of inheritance. The incidence is estimated to be approximately 1 in 100,000 live births. The liver lesion proved to be variable, with
B Plecko et al.
Annals of neurology, 48(1), 121-125 (2000-07-14)
Diagnosis of pyridoxine-dependent epilepsy is based on the clinical response to high-dosage application of pyridoxine. Here, we report on 2 patients with pyridoxine-dependent epilepsy with significant elevation of pipecolic acid concentrations in plasma and cerebrospinal fluid (CSF) and further increase