Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Cambiar Vistas
Acerca de este artículo
Fórmula empírica (notación de Hill):
C45H94N3O19P3
Número CAS:
Peso molecular:
1074.16
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarleNombre del producto
18:1 PI(3,4)P2, 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt), powder
assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 100 μg (with stopper and crimp cap (850153P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850153P-500ug))
manufacturer/tradename
Avanti Research™ - A Croda Brand 850153P
lipid type
phospholipids
cardiolipins
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP(O[C@H]1[C@H](O)[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](OP(O)([O-])=O)[C@H]1O)([O-])=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+].[NH4+].[NH4+]
General description
18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate)) is an ammonium salt of modified lipid.
Inositol phospholipid species are membrane-bound signaling molecules that have been implicated in almost all aspects of cellular physiology, including cellular growth, metabolism, proliferation, and survival.
Application
18:1 PI(3,4)P2 (1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt)) has been used:
- in liposomes/supported lipid bilayer preparation
- in liposome co-sedimentation
- in the preparation of anionic phospholipid liposomes
Biochem/physiol Actions
PI(3,4)P2 can act as a lipid second messenger. In mast cells, PI(3,4)P2 plays a key role in protein kinase B (PKB) phosphorylation on Ser473 sites.
Packaging
2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-500ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (850153P-100ug)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Clase de almacenamiento
11 - Combustible Solids
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Kewei Ma et al.
Cellular signalling, 20(4), 684-694 (2008-02-06)
The PI3K-PKB pathway is an important and widely studied pathway in cell signaling. The enzyme activity of PI3K produces D-3 phosphoinositides, including the lipid second messengers PI(3,4,5)P3 and PI(3,4)P2. PI(3,4,5)P3 has been deemed to be the most important second messenger
Arthur P H de Jong et al.
Neuron, 98(2), 335-349 (2018-04-03)
Rapid and efficient synaptic vesicle fusion requires a pool of primed vesicles, the nearby tethering of Ca2+ channels, and the presence of the phospholipid PIP2 in the target membrane. Although the presynaptic active zone mediates the first two requirements, it
Iris K Jarsch et al.
The Journal of cell biology, 219(4) (2020-04-25)
Filopodia are finger-like actin-rich protrusions that extend from the cell surface and are important for cell-cell communication and pathogen internalization. The small size and transient nature of filopodia combined with shared usage of actin regulators within cells confounds attempts to