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Merck

860519P

Avanti

C18:1 Ceramide (d18:1/18:1(9Z))

Avanti Research - A Croda Brand

Sinónimos:

N-oleoyl-D-erythro-sphingosine

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Acerca de este artículo

Fórmula empírica (notación de Hill):
C36H69NO3
Número CAS:
Peso molecular:
563.94
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
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Nombre del producto

C18:1 Ceramide (d18:1/18:1(9Z)), Avanti Research - A Croda Brand 860519P, powder

assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 25 mg (860519P-25mg), pkg of 1 × 5 mg (860519P-5mg)

manufacturer/tradename

Avanti Research - A Croda Brand 860519P

lipid type

sphingolipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

OC[C@]([H])(NC(CCCCCCC/C=C\CCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C36H69NO3/c1-3-5-7-9-11-13-15-17-18-20-22-24-26-28-30-32-36(40)37-34(33-38)35(39)31-29-27-25-23-21-19-16-14-12-10-8-6-4-2/h17-18,29,31,34-35,38-39H,3-16,19-28,30,32-33H2,1-2H3,(H,37,40)/b18-17-,31-29+/t34-,35+/m0/s1

InChI key

OBFSLMQLPNKVRW-RHPAUOISSA-N

General description

C18:1 Ceramide (d18:1/18:1(9Z)) or N-oleoyl-D-erythro-sphingosine is a synthetic ceramide containing sphingosine with oleic acid.

Application

C18:1 Ceramide (d18:1/18:1(9Z)) may be used as a standard:
  • to quantify ceramide content in muscle tissue samples using high-performance liquid chromatography/tandem mass spectrometry (HPLC/MS2)
  • for the absolute quantification of epidermal lipids using liquid chromatography-tandem mass spectrometry (LC/MS/MS)
  • for the ratiometric quantification of sphingomyelin (SM)

Packaging

5 mL Amber Glass Screw Cap Vial (860519P-25mg)
5 mL Amber Glass Screw Cap Vial (860519P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Meenu N Perera et al.
Biochimica et biophysica acta, 1818(5), 1291-1301 (2012-03-01)
The sphingolipid, ceramide, self-assembles in the mitochondrial outer membrane (MOM), forming large channels capable of translocating proteins. These channels are believed to be involved in protein release from mitochondria, a key decision-making step in cell death. Synthetic analogs of ceramide
Ayman J Aljohani et al.
Investigative ophthalmology & visual science, 55(6), 3413-3422 (2014-05-03)
We determined the profiles of sphingomyelin, sphingoid base, sphingoid base-1-phosphate, and ceramide, and their quantitative differences between control and glaucomatous trabecular meshwork (TM) derived from human donors. Control and primary open angle glaucoma (POAG) TM samples were collected from cadaver
Daniel A Peñalva et al.
Biochimica et biophysica acta, 1838(3), 731-738 (2013-12-10)
Unique species of ceramide (Cer) with very-long-chain polyunsaturated fatty acid (VLCPUFA), mainly 28-32 carbon atoms, 4-5 double bonds, in nonhydroxy and 2-hydroxy forms (n-V Cer and h-V Cer, respectively), are generated in rat spermatozoa from the corresponding sphingomyelins during the