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>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (880128P-10mg), pkg of 1 × 100 mg (880128P-100mg), pkg of 1 × 25 mg (880128P-25mg), pkg of 1 × 50 mg (880128P-50mg), pkg of 1 × 500 mg (880128P-500mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\N)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.
General description
DSPE-PEG(2000) is a 18-carbon acyl chain containing phospholipid with a critical micelle concentration of 1× 106 M. It is conjugated with functional groups like biotin, primary amine and carboxylic acid. The micelles display spheroid shape with a size of 18mm.
Application
DSPE-PEG(2000) Amine has been used:
- for the generation of single-walled carbon nanotubes (SWNTs) phospholipid-polyethylene glycol-folic acid conjugate
- in the preparation of polyethylene glycol (PEGylated) magnetic nanoparticles based liposomes
- in the preparation of liposomes for myomerger ectodomain based disruption studies
Biochem/physiol Actions
DSPE-PEG(2000) micelles aids in the solubilization of hydrophobic drugs and their delivery. It is used for coating of magnetic iron oxide-based nanoparticles.
Packaging
20 mL Clear Glass Screw Cap Vial (880128P-500mg)
5 mL Amber Glass Screw Cap Vial (880128P-100mg)
5 mL Amber Glass Screw Cap Vial (880128P-10mg)
5 mL Amber Glass Screw Cap Vial (880128P-25mg)
5 mL Amber Glass Screw Cap Vial (880128P-50mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
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Functionalization and peptide-based delivery of magnetic nanoparticles as an intracellular MRI contrast agent
Nitin N, et al.
Journal of Biological Inorganic Chemistry, 9(6), 706-712 (2004)
Thermodynamic and kinetic stability of DSPE-PEG (2000) micelles in the presence of bovine serum albumin
Kastantin M, et al.
The Journal of Physical Chemistry B, 114(39), 12632-12640 (2010)
Enhanced blood-brain barrier transmigration using a novel transferrin embedded fluorescent magneto-liposome nanoformulation
Ding H, et al.
Nanotechnology, 25(5), 055101-055101 (2014)