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Merck

LM1504

Avanti

17:0-14:1 PI

Avanti Research - A Croda Brand

Sinónimos:

1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) (ammonium salt)

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Fórmula empírica (notación de Hill):
C40H78NO13P
Número CAS:
Peso molecular:
812.02
UNSPSC Code:
12352211
NACRES:
NA.25
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Nombre del producto

17:0-14:1 PI, Avanti Research - A Croda Brand LM1504, methanol solution

assay

>99% (TLC)

form

methanol solution

packaging

pkg of 1 × 1 mL (LM1504-1EA)

manufacturer/tradename

Avanti Research - A Croda Brand LM1504

concentration

~10 μg/mL (Refer to C of A for lot specific concentration. )

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](O)[C@H]1O)=O)(OC(CCCCCCC/C=C\CCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

InChI key

VDNRHLFKICVCHS-ATJCMGOSSA-N

Application

17:0-14:1 PI or 1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-(1′-myo-inositol) has been used as an internal standard for:
  • the detection of phosphatidylinositol class of lipids by tandem mass spectrometry (MS/MS) analysis
  • phospholipid quantification by MS analysis
  • lipid analysis of murine brain lipid extract using Fourier transform-ion cyclotron resonance-mass spectrometry (FT-ICR-MS)

Packaging

2 mL Amber Glass Sealed Ampule (LM1504-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup



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Matthew W Granger et al.
Journal of neurochemistry, 149(4), 499-517 (2018-07-25)
Changes in glycerophosphocholine metabolism are observed in Alzheimer's disease; however, it is not known whether these metabolic disruptions are linked to cognitive decline. Here, using unbiased lipidomic approaches and direct biochemical assessments, we profiled Land's cycle lipid remodeling in the
Andreas Ullen et al.
Free radical biology & medicine, 49(11), 1655-1665 (2010-09-03)
Plasmalogens, 1-O-alk-1'-enyl-2-acyl-sn-glycerophospholipids, are significant constituents of cellular membranes and are essential for normal brain development. Plasmalogens, which contain a vinyl ether bond at the sn-1 position, are preferential targets for hypochlorous acid (HOCl), generated by myeloperoxidase (MPO) from H(2)O(2) and
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced