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Acerca de este artículo
Fórmula empírica (notación de Hill):
C35H69NO3
Número CAS:
Peso molecular:
551.93
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Servicio técnico
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Permítanos ayudarleassay
>99% (TLC)
form
powder
packaging
pkg of 1 × 10 mg (860517P-10mg), pkg of 1 × 25 mg (860517P-25mg), pkg of 1 × 5 mg (860517P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@]([H])(NC(CCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC
InChI
1S/C35H69NO3/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-35(39)36-33(32-37)34(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h28,30,33-34,37-38H,3-27,29,31-32H2,1-2H3,(H,36,39)/b30-28+/t33-,34+/m0/s1
InChI key
ICWGMOFDULMCFL-QKSCFGQVSA-N
General description
Ceramide synthesis is mediated either by the salvage pathway by the acylation of sphingosine or sphingolipids hydrolysis or by de novo pathway via dihydroceramide formation. Structurally, ceramides have a sphingoid base, a long-chain amino alcohol linked to fatty acid by an amide bond.
Application
C17 Ceramide (d18:1/17:0) has been used:
- as an internal standard for myocardial ceramide quantification using chromatography with negative ion electrospray ionization coupled to tandem mass spectrometry
- as an internal standard in tandem mass spectrometry (MS/MS)
- as a substrate for sphingomyelin synthase 2 enzyme
Biochem/physiol Actions
Ceramides play a key role in regulating various cellular processes like senescence and apoptosis. They are directly involved in the proliferation and differentiation of skin cells and regulate skin barrier functionality. Ceramide based analogs are potential anti-tumor agents and are regarded as tumor suppressor lipid.
Packaging
5 mL Amber Glass Screw Cap Vial (860517P-10mg)
5 mL Amber Glass Screw Cap Vial (860517P-25mg)
5 mL Amber Glass Screw Cap Vial (860517P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
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