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Merck

07-130

Anti-Ezrin Antibody

Upstate®, from rabbit

Sinónimos:

Anti-CVIL, Anti-CVL, Anti-HEL-S-105, Anti-VIL2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Nombre del producto

Anti-Ezrin Antibody, Upstate®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_003379

UniProt accession no.

P15311

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

mouse ... Ezr(22350)

Preparation Note

2 years at -20°C

Analysis Note

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for mingels.
routinely evaluated by immunoblot on RIPA lysates from A431 cells or a mouse brain lysate

Application

Research Category
Cell Structure
Research Sub Category
Cytoskeleton
This Anti-Ezrin Antibody is validated for use in WB, IH for the detection of Ezrin.

Biochem/physiol Actions

Ezrin

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

81kDa
Ezrin is also referred to as Villin-2 and Cytovillin

Immunogen

peptide corresponding to amino acids 479-498 of human Ezrin (C-EPVSYHVQESLQDEGAEPTG)

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A chromatography

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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Calpain regulates enterocyte brush border actin assembly and pathogenic Escherichia coli-mediated effacement
Potter, D. A., et al
The Journal of Biological Chemistry, 278, 30403-30412 (2003)
Proteomics analysis of the ezrin interactome in B cells reveals a novel association with Myo18a?.
Ken Matsui,Neetha Parameswaran,Nayer Bagheri,Belinda Willard,Neetu Gupta
Journal of Proteome Research null
Ana Cicvaric et al.
Annals of medicine, 48(8), 652-668 (2016-08-26)
Podoplanin is a cell-surface glycoprotein constitutively expressed in the brain and implicated in human brain tumorigenesis. The intrinsic function of podoplanin in brain neurons remains however uncharacterized. Using an established podoplanin-knockout mouse model and electrophysiological, biochemical, and behavioral approaches, we
Myc down-regulation as a mechanism to activate the Rb pathway in STAT5A-induced senescence.
Mallette, FA; Gaumont-Leclerc, MF; Huot, G; Ferbeyre, G
The Journal of Biological Chemistry null
Hai-Su Yang et al.
Molecular cell, 11(5), 1163-1176 (2003-05-29)
Passage of normal cells in culture leads to senescence, an irreversible cell cycle exit characterized by biochemical changes and a distinctive morphology. Cellular stresses, including oncogene activation, can also lead to senescence. Consistent with an anti-oncogenic role for this process
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SKUGTIN
07-13004053252743658

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