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Merck

577801

Anti-Tau Mouse mAb (TAU-5)

liquid, clone TAU-5, Calbiochem®

Sinónimos:

Anti-Tau antibody

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NACRES:
NA.43
UNSPSC Code:
12352203

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Nombre del producto

Anti-Tau Mouse mAb (TAU-5), liquid, clone TAU-5, Calbiochem®

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

TAU-5, monoclonal

form

liquid

does not contain

preservative

species reactivity

mouse, human, sheep, rat

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(Frozen Sections (1-2 µg/mL)
Immunoblotting (1 µg/mL)
Immunoprecipitation (10 µg per 200-500 µg cell lysate)
Paraffin Sections (1-2 µg/mL, heat pre-treatment required))

isotype

IgG1

shipped in

wet ice

storage temp.

−70°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... MAPT(4137)
mouse ... Mapt(17762)
rat ... Mapt(29477)

Application

Frozen Sections (1-2 µg/ml)

Immunoblotting (1 µg/ml)

Immunoprecipitation (10 µg per 200-500 µg cell lysate)

Paraffin Sections (1-2 µg/ml, heat pre-treatment required)

Disclaimer

Toxicity: Standard Handling (A)

General description

Protein G purified mouse monoclonal antibody. Recognizes the ~45-68 kDa phosphorylated and unphosphorylated forms of tau.
Recognizes the ~45-68 kDa Tau protein.
This Anti-Tau Mouse mAb (TAU-5) is validated for use in Frozen Sections, Immunoblotting, Immunoprecipitation, Paraffin Sections for the detection of Tau.

Immunogen

Bovine
Epitope: within the central region
purified bovine microtubule-associated proteins

Other Notes

Papasozomenos, S.C. and Shanavas, A., 2002. Proc. Natl. Acad. Sci. USA99, 1140.
Rapoport, M., eta al. 2002. Proc. Natl. Acad. Sci. USA99, 6364.
When used for formalin/paraffin embedded sections, staining is enhanced by boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at room temperature for 20 min prior to antibody incubation. Alternate splicing of tau mRNA and differential phosphorylation contribute to the heterogeneity of tau. Does not cross-react with other MAPS of tubulin. Recognizes both native and phosphorylated forms of tau. Variables associated with assay conditions will dictate proper working dilution.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In PBS.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C). Do not store diluted antibody without carrier protein if the concentration is <50 µg/ml.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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