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Merck

AB1528SP

Anti-Nerve Growth Factor-β Antibody

Chemicon®, from sheep

Sinónimos:

NGFbeta

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IHC, WB
Citations:
10
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biological source

sheep

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

chicken, human, rat, mouse

should not react with

bovine

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... NGF(4803)

Immunogen

Mouse nerve growth factor-beta purified from salivary glands. Antigen purity greater than 95% by PAGE.

Application

Anti-Nerve Growth Factor-β Antibody is an antibody against Nerve Growth Factor-β for use in ELISA, WB, IH.
Immunohistochemistry: 1-10 μg/mL (see suggested protocol).

Immunoblotting: 1-10 μg/mL

ELISA: 1-10 μg/mL

Inhibition of biological activity in vitro: 1-10 μg/mL
BIOLOGICAL ACTIVITY: Neutralizes NGF, but not other neurotrophins.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Biochem/physiol Actions

Nerve growth factor-beta (NGF). By one site ELISA, less than 1% cross-reactivity against recombinant human BDNF or neurotrophin 4. Approximately 2% cross-reactivity against neurotrophin 3.

Physical form

Format: Purified
Protein G purified immunoglobulin. Lyophilized from PBS, no preservatives. Reconstitute with 500 μL of sterile distilled water (1 mg/mL).

Preparation Note

Maintain at -20 to -70°C in undiluted aliquots for up to one year. Avoid repeated freeze/thaw cycles. Glycerol (1:1) can be added for additional stability.

Other Notes

Replaces: 04-1119

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Sravya Kurapati et al.
Journal of virology, 91(17) (2017-06-24)
Mechanisms of neuronal infection by varicella-zoster virus (VZV) have been challenging to study due to the relatively strict human tropism of the virus and the paucity of tractable experimental models. Cellular mitogen-activated protein kinases (MAPKs) have been shown to play
Tomohiko Sadaoka et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(17), E2403-E2412 (2016-04-15)
Varicella-zoster virus (VZV) establishes latency in human sensory and cranial nerve ganglia during primary infection (varicella), and the virus can reactivate and cause zoster after primary infection. The mechanism of how the virus establishes and maintains latency and how it
The role of mesopontine NGF in sleep and wakefulness.
Ramos, OV; Torterolo, P; Lim, V; Chase, MH; Sampogna, S; Yamuy, J
Brain Research null
Ming-Shian Tsai et al.
Experimental & molecular medicine, 50(1), e426-e426 (2018-01-13)
This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in human livers with hepatolithiasis and the effects of NGF therapy
Martin Larhammar et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(46), 11074-11084 (2017-10-11)
The c-Jun-N-terminal kinase (JNK) signaling pathway regulates nervous system development, axon regeneration, and neuronal degeneration after acute injury or in chronic neurodegenerative disease. Dual leucine zipper kinase (DLK) is required for stress-induced JNK signaling in neurons, yet the factors that

Número de artículo de comercio global

SKUGTIN
AB1528SP04053252370939

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