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Merck

MAB4315

Anti-STRO-1 Antibody, clone STRO-1

ascites fluid, clone STRO-1, Chemicon®

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
STRO-1, monoclonal
Species reactivity:
human, primate
Application:
FACS, IF
Citations:
21

Documentos clave

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biological source

mouse

antibody form

ascites fluid

antibody product type

primary antibodies

clone

STRO-1, monoclonal

species reactivity

human, primate

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable, immunofluorescence: suitable

input

sample type mesenchymal stem cell(s)

isotype

IgM

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Categorías relacionadas

General description

STRO-1 is a cell surface protein expressed by bone marrow stromal cells and erythroid precursors. The frequency of colony forming units fibroblasts (CFU-F) was enriched 100-fold in the STRO-1+/Glycophorin A- population from bone marrow cells. The subset of marrow cells that expresses the STRO-1 antigen is capable of differentiating into multiple mesenchymal lineages including hematopoiesis-supportive stromal cells with a vascular smooth muscle-like phenotype, adipocytes, osteoblasts, and chondrocytes.

Immunogen

CD34+ bone marrow cells

Application

Detect STRO-1 using this Anti-STRO-1 Antibody, clone STRO-1 validated for use in FC & IF.

Biochem/physiol Actions

Recognizes a cell surface antigen expressed by bone marrow stromal cells and stromal precursors. STRO-1 binds to approximately 10% of bone marrow mononuclear cells, greater than 95% of which are nucleated erythroid precursors.

Analysis Note

Control
Bone marrow cultures

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

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Jeong Seok Lee et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 34(5), 1824-1834 (2014-12-17)
Mussel-inspired polydopamine (PDA) is known to be an effective bioadhesive and bioactive material for controlling stem cell fate, which is important in stem cell-based regenerative medicine; however, the effect of PDA on osteogenic differentiation of periodontal ligament stem cells (PDLSCs)
Yiping Fan et al.
PloS one, 5(12), e14421-e14421 (2011-01-05)
Mammary stem cells have been extensively studied as a system to delineate the pathogenesis and treatment of breast cancer. However, research on mammary stem cells requires tissue biopsies which limit the quantity of samples available. We have previously identified putative
Srinivas Velugotla et al.
Biomicrofluidics, 6(4), 44113-44113 (2012-01-01)
Assessment of the dielectrophoresis (DEP) cross-over frequency (f xo), cell diameter, and derivative membrane capacitance (C m) values for a group of undifferentiated human embryonic stem cell (hESC) lines (H1, H9, RCM1, RH1), and for a transgenic subclone of H1
Samuel Joshua Pragasam Sampath et al.
Stem cell investigation, 8, 5-5 (2021-04-09)
Mesenchymal stem cells (MSCs) have gained wide therapeutic acceptance in regenerative medicine due to their potential in repair process in restoring the damaged tissues and controlling inflammation. In the present study, we report for the first time the beneficial effects
Multipotent properties of myofibroblast cells derived from human placenta.
Strakova, Z; Livak, M; Krezalek, M; Ihnatovych, I
Cell and Tissue Research null
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Contenido relacionado

Human Stem Cell Systems

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

MOUSE ANTI-STRO-1 MONOCLONAL ANTIBODY

Número de artículo de comercio global

SKUGTIN
MAB431504053252579967

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