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Merck

01-0870

N-Acetyl-L-cysteine

SAJ special grade, 98.0-102.0%

Sinónimos:

LNAC, NAC

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Fórmula lineal:
HSCH2CH(NHCOCH3)CO2H
Número CAS:
Peso molecular:
163.19
EC Number:
210-498-3
UNSPSC Code:
12352209
PubChem Substance ID:
Beilstein/REAXYS Number:
1724426
MDL number:
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grade

SAJ special grade

assay

98.0-102.0%

form

solid

availability

available only in Japan

mp

106-108 °C (lit.)

application(s)

peptide synthesis

shipped in

wet ice

storage temp.

2-8°C

SMILES string

CC(=O)N[C@@H](CS)C(O)=O

InChI

1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1

InChI key

PWKSKIMOESPYIA-BYPYZUCNSA-N

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.


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Hazard Classifications

Eye Irrit. 2

Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Michael Berk et al.
Trends in pharmacological sciences, 34(3), 167-177 (2013-02-02)
N-Acetylcysteine (NAC) targets a diverse array of factors germane to the pathophysiology of multiple neuropsychiatric disorders including glutamatergic transmission, the antioxidant glutathione, neurotrophins, apoptosis, mitochondrial function, and inflammatory pathways. This review summarises the areas where the mechanisms of action of