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Merck

34087

Diethofencarb

PESTANAL®, analytical standard

Sinónimos:

Isopropyl N-(3,4-diethoxyphenyl)carbamate

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Fórmula empírica (notación de Hill):
C14H21NO4
Número CAS:
Peso molecular:
267.32
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
403-870-3
MDL number:
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InChI

1S/C14H21NO4/c1-5-17-12-8-7-11(9-13(12)18-6-2)15-14(16)19-10(3)4/h7-10H,5-6H2,1-4H3,(H,15,16)

InChI key

LNJNFVJKDJYTEU-UHFFFAOYSA-N

SMILES string

CCOc1ccc(NC(=O)OC(C)C)cc1OCC

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

Quality Level

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General description

Diethofencarb is a systemic, phenyl-carbamate fungicide, used for the control of gray mold on fruits and vegetables. Its mode of action involves the inhibition of phospholipids and fatty acid biosynthesis in pathogens.

Application

Diethofencarb may be used as an analytical reference standard for the determination of the analyte in peel and pulp of apples using dispersive liquid-liquid microextraction, followed by high-performance liquid chromatography with diode-array detection (HPLC-DAD).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Hirokazu Tarui et al.
Journal of agricultural and food chemistry, 52(3), 538-544 (2004-02-05)
Rats were orally given a diethofencarb (isopropyl 3,4-diethoxyphenylcarbamate) labeled with (14)C, at 300 mg/kg/day, for 4 consecutive days, and 11 metabolites in urine were purified by a combination of several chromatographic techniques. The chemical structures of all isolated metabolites were
M Fujimura et al.
Current genetics, 25(5), 418-422 (1994-05-01)
We have previously shown that increased sensitivity to diethofencarb in the carbendazim(MBC)-resistant F914 strain of Neurospora crassa is caused by a single amino-acid change in beta-tubulin, 198Glu to Gly. Three diethofencarb-resistant mutants that are also resistant to MBC were isolated
Xiu-Min Yang et al.
Journal of chromatographic science, 46(8), 751-756 (2008-09-18)
A method for the determination of metolcarb and diethofencarb in apples and apple juice is developed using solid-phase microextraction (SPME) coupled with high-performance liquid chromatography (HPLC). The experimental conditions of SPME, such as the kind of extraction fiber, extraction time
S Hosokawa et al.
The Journal of toxicological sciences, 17(3), 155-166 (1992-08-01)
To examine the mechanism and toxicological significance of thyroidal tumor observed slightly in a long-term rat study with diethofencarb (isopropyl 3,4-diethoxycarbanilate), male Sprague-Dawley rats were fed diethofencarb in diets at concentrations of 0, 5,000 or 20,000 ppm for 3 months.
Jing Cheng et al.
International journal of environmental analytical chemistry, 90(11), 845-855 (2010-09-24)
Dispersive liquid-liquid microextraction (DLLME) has been developed for the extraction and preconcentration of diethofencarb (DF) and pyrimethanil (PM) in environmental water. In the method, a suitable mixture of extraction solvent (50 μL carbon tetrachloride) and dispersive solvent (0.75 mL acetonitrile)

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