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PHR1748

Ácido acético

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Ácido acético glacial

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Fórmula lineal:
CH3CO2H
Número CAS:
64-19-7
Peso molecular:
60.05
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329823593
EC Number:
200-580-7
Beilstein/REAXYS Number:
506007
MDL number:
MFCD00036152
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Quality Segment

300

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to USP 1005706

vapor density

2.07 (vs air)

API family

glacial acetic acid

CofA

current certificate can be downloaded

autoignition temp.

800 °F

expl. lim.

16 %, 92 °F, 4 %, 59 °F

packaging

ampule of 3x1.5 mL

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

refractive index

n20/D 1.371 (lit.)

bp

117-118 °C (lit.)

mp

16.2 °C (lit.)

density

1.04 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

SMILES string

[F2C(F2C)13F3C]C(O)=O

InChI

1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)

InChI key

QTBSBXVTEAMEQO-UHFFFAOYSA-N

General description

Glacial Acetic Acid is a simple monocarboxylic acid, which is devoid of water. Pharmaceutically, it is commonly used as a topical antibiotic that treats infections caused by bacteria.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Glacial Acetic Acid may be used as a reference standard for the determination of the analyte in raw materials and pharmaceutical formulations by titrimetry and gas chromatography.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC2954 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

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pictograms

FlameCorrosion
GHS02,GHS05

signalword

Danger

hcodes

H226,H314

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A

Clase de almacenamiento

3 - Flammable liquids

wgk

WGK 1

flash_point_f

102.2 °F - closed cup

flash_point_c

39 °C - closed cup

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Visite la Librería de documentos

Quantitative analysis of volatile fatty acids in aqueous solution by gas chromatography
Mahadevan V and Stenroos L
Analytical Chemistry, 39(13), 1652-1654 (1967)
Glacial Acetic Acid
USP43/NF38: United States Pharmacopei and National Formulary
United States Pharmacopeia/National Formulary, 36(3), 77-77 (2018)
Part 5: Pharmaceutical Manufacturing
Remington: The Science and Practice of Pharmacy, 1083-1083 (2005)
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