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Merck

PHR1848

Cephalexin

Pharmaceutical Secondary Standard; Certified Reference Material

Sinónimos:

Cephalexin monohydrate

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Fórmula empírica (notación de Hill):
C16H17N3O4S · H2O
Número CAS:
Peso molecular:
365.40
UNSPSC Code:
41116107
EC Number:
239-773-6
NACRES:
NA.24
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Quality Segment

grade

certified reference material, pharmaceutical secondary standard

agency

traceable to Ph. Eur. C0675000, traceable to USP 1099008

API family

cephalexin

CofA

current certificate can be downloaded

packaging

pkg of 1 g

application(s)

pharmaceutical

format

neat

storage temp.

2-30°C

SMILES string

S1[C@H]2N(C(=C(C1)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3.O

InChI

1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1

InChI key

AVGYWQBCYZHHPN-CYJZLJNKSA-N

General description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Cephalexin is a cephalosporine which is categorized under the class of β-lactam antibiotics. It is utilized for regulating the effects of Gram-positive and Gram-negative bacteria. It favors the lysis of bacterial cell wall by inhibiting the synthesis of essential structural components. Cephalexin belongs to the safest group of broad-spectrum bactericidal antimicrobial agents.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Cephalexin may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and water samples by various chromatography techniques.

Analysis Note

These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.

Other Notes

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAC0286 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Determination of multiple pharmaceutical classes in surface and ground waters by liquid chromatography-ion trap-tandem mass spectrometry.
Grujic S, et al.
Journal of Chromatography A, 1216(25), 4989-5000 (2009)
Comparison of several methods used for the determination of cephalosporins. Analysis of cephalexin in pharmaceutical samples.
Martinez LG, et al.
Journal of Pharmaceutical and Biomedical Analysis, 29(3), 405-423 (2002)
Rapid and sensitive high-performance liquid chromatographic determination of four cephalosporin antibiotics in pharmaceuticals and body fluids.
Samanidou VF, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 788(1), 147-158 (2003)